{
  "schemaVersion": 1,
  "kind": "state-of-peptides",
  "month": "2026-10",
  "title": "State of Peptides: October 2026",
  "generatedAt": "2026-10-24T22:32:46.624Z",
  "coverage": {
    "from": "2026-10-01",
    "through": "2026-10-22",
    "days": 22,
    "daysInMonth": 31,
    "partial": true
  },
  "corpus": {
    "posts": 6830,
    "prevPosts": 9501,
    "perDay": 310.5,
    "prevPerDay": 316.7,
    "postsWithText": 4653,
    "subreddits": [
      {
        "name": "Retatrutide",
        "posts": 2297
      },
      {
        "name": "tirzepatidecompound",
        "posts": 1551
      },
      {
        "name": "Biohackers",
        "posts": 1348
      },
      {
        "name": "Semaglutide",
        "posts": 443
      },
      {
        "name": "Peptides",
        "posts": 430
      },
      {
        "name": "Peptidesource",
        "posts": 405
      },
      {
        "name": "Nootropics",
        "posts": 216
      },
      {
        "name": "longevity",
        "posts": 51
      },
      {
        "name": "PeptideGuide",
        "posts": 50
      },
      {
        "name": "PeptideDiscussion",
        "posts": 39
      }
    ],
    "trendMonths": [
      "2026-05",
      "2026-06",
      "2026-07",
      "2026-08",
      "2026-09",
      "2026-10"
    ]
  },
  "captions": {
    "by": "mixed",
    "model": "gemini-3.8-flash",
    "sections": {
      "mentions": "Through day 22, the 10 subreddits averaged 310.5 posts a day in October 2026, compared to 316.7 in September 2026. Retatrutide, Tirzepatide, Semaglutide led discussions.",
      "rising": "Compared to September 2026, Glutathione was up 28%, Tirzepatide was up 8%, and Semaglutide was up 4% in post share.",
      "sideEffects": "Among posts discussing each compound, Nausea appeared in 2.7% of Tirzepatide posts and 6.7% of Retatrutide posts.",
      "doses": "For dose discussions, 1 mg led Retatrutide posts at 20.7%, while 5 mg led Tirzepatide posts at 17.2%.",
      "newCompounds": "Eloralintide reached 11 posts this month after quiet discussion across the prior 5 months.",
      "questions": "Across 1,585 posts with questions, Dosing led at 16.3%, followed by Side effects at 12.2%."
    }
  },
  "headlines": [
    {
      "id": "top-compound",
      "section": "mentions",
      "text": "Retatrutide led October 2026 discussions with 2,479 posts, appearing in 363 of every 1,000 posts.",
      "facts": {
        "compound": "Retatrutide",
        "month": "October 2026",
        "mentions": "2,479",
        "per1000": "363",
        "thousand": "1,000"
      }
    },
    {
      "id": "fastest-rising",
      "section": "rising",
      "text": "Glutathione was up 28% from 4 to 5.1 per 1,000 posts compared to September 2026.",
      "facts": {
        "compound": "Glutathione",
        "per1000": "5.1",
        "previousPer1000": "4",
        "change": "up 28%",
        "previousMonth": "September 2026",
        "thousand": "1,000"
      }
    },
    {
      "id": "side-effect-shift",
      "section": "sideEffects",
      "text": "Tirzepatide posts discussing Nausea were down 1.7 points from 4.4% in September 2026 to 2.7%.",
      "facts": {
        "compound": "Tirzepatide",
        "effect": "Nausea",
        "share": "2.7%",
        "previousShare": "4.4%",
        "change": "down 1.7 points",
        "previousMonth": "September 2026"
      }
    },
    {
      "id": "dose-shift",
      "section": "doses",
      "text": "Mentions of 10 mg were down 1.5 points to 8.3% of Tirzepatide dose posts from 9.8% in September 2026.",
      "facts": {
        "compound": "Tirzepatide",
        "amount": "10 mg",
        "share": "8.3%",
        "previousShare": "9.8%",
        "change": "down 1.5 points",
        "previousMonth": "September 2026"
      }
    },
    {
      "id": "new-compound",
      "section": "newCompounds",
      "text": "Eloralintide recorded 11 posts in October 2026 after averaging 0.2 a day over the past 5 months.",
      "facts": {
        "compound": "Eloralintide",
        "mentions": "11",
        "month": "October 2026",
        "priorPerDay": "0.2",
        "five": "5"
      }
    },
    {
      "id": "top-question",
      "section": "questions",
      "text": "Dosing led October 2026 inquiries, making up 16.3% of 1,585 posts with questions.",
      "facts": {
        "topic": "Dosing",
        "share": "16.3%",
        "questions": "1,585",
        "month": "October 2026"
      }
    }
  ],
  "press": [
    {
      "headline": "Retatrutide leads Reddit peptide discussions in October 2026",
      "angle": "Retatrutide led with 2,479 posts or 363 per 1,000, while Tirzepatide reached 265.2 in October 2026.",
      "facts": {
        "compound": "Retatrutide",
        "month": "October 2026",
        "mentions": "2,479",
        "per1000": "363",
        "thousand": "1,000",
        "secondCompound": "Tirzepatide",
        "secondPer1000": "265.2"
      }
    },
    {
      "headline": "Glutathione discussions rise 28% on Reddit forums",
      "angle": "Its share of posts went from 4 to 5.1 per 1,000 between September 2026 and October 2026.",
      "facts": {
        "compound": "Glutathione",
        "per1000": "5.1",
        "previousPer1000": "4",
        "change": "up 28%",
        "previousMonth": "September 2026",
        "thousand": "1,000",
        "month": "October 2026"
      }
    },
    {
      "headline": "Tirzepatide discussions shift away from 10 mg dose",
      "angle": "Mentions of 10 mg were down 1.5 points from 9.8% in September 2026 to 8.3% in October 2026.",
      "facts": {
        "compound": "Tirzepatide",
        "amount": "10 mg",
        "share": "8.3%",
        "previousShare": "9.8%",
        "change": "down 1.5 points",
        "previousMonth": "September 2026",
        "month": "October 2026"
      }
    }
  ],
  "compounds": [
    {
      "slug": "retatrutide",
      "name": "Retatrutide",
      "inDataset": true,
      "rank": 1,
      "mentions": 2479,
      "perDay": 112.7,
      "per1000": 363,
      "prevMentions": 3579,
      "prevPerDay": 119.3,
      "prevPer1000": 376.7,
      "paceChangePct": -6,
      "shareChangePct": -4,
      "series": [
        {
          "month": "2026-05",
          "days": 31,
          "mentions": 5951,
          "perDay": 192,
          "per1000": 355.6
        },
        {
          "month": "2026-06",
          "days": 30,
          "mentions": 5230,
          "perDay": 174.3,
          "per1000": 384
        },
        {
          "month": "2026-07",
          "days": 31,
          "mentions": 5029,
          "perDay": 162.2,
          "per1000": 390.8
        },
        {
          "month": "2026-08",
          "days": 31,
          "mentions": 4684,
          "perDay": 151.1,
          "per1000": 394.2
        },
        {
          "month": "2026-09",
          "days": 30,
          "mentions": 3579,
          "perDay": 119.3,
          "per1000": 376.7
        },
        {
          "month": "2026-10",
          "days": 22,
          "mentions": 2479,
          "perDay": 112.7,
          "per1000": 363
        }
      ]
    },
    {
      "slug": "tirzepatide",
      "name": "Tirzepatide",
      "inDataset": true,
      "rank": 2,
      "mentions": 1811,
      "perDay": 82.3,
      "per1000": 265.2,
      "prevMentions": 2322,
      "prevPerDay": 77.4,
      "prevPer1000": 244.4,
      "paceChangePct": 6,
      "shareChangePct": 8,
      "series": [
        {
          "month": "2026-05",
          "days": 31,
          "mentions": 3882,
          "perDay": 125.2,
          "per1000": 232
        },
        {
          "month": "2026-06",
          "days": 30,
          "mentions": 2808,
          "perDay": 93.6,
          "per1000": 206.2
        },
        {
          "month": "2026-07",
          "days": 31,
          "mentions": 3010,
          "perDay": 97.1,
          "per1000": 233.9
        },
        {
          "month": "2026-08",
          "days": 31,
          "mentions": 2698,
          "perDay": 87,
          "per1000": 227.1
        },
        {
          "month": "2026-09",
          "days": 30,
          "mentions": 2322,
          "perDay": 77.4,
          "per1000": 244.4
        },
        {
          "month": "2026-10",
          "days": 22,
          "mentions": 1811,
          "perDay": 82.3,
          "per1000": 265.2
        }
      ]
    },
    {
      "slug": "semaglutide",
      "name": "Semaglutide",
      "inDataset": true,
      "rank": 3,
      "mentions": 596,
      "perDay": 27.1,
      "per1000": 87.3,
      "prevMentions": 795,
      "prevPerDay": 26.5,
      "prevPer1000": 83.7,
      "paceChangePct": 2,
      "shareChangePct": 4,
      "series": [
        {
          "month": "2026-05",
          "days": 31,
          "mentions": 1429,
          "perDay": 46.1,
          "per1000": 85.4
        },
        {
          "month": "2026-06",
          "days": 30,
          "mentions": 1168,
          "perDay": 38.9,
          "per1000": 85.8
        },
        {
          "month": "2026-07",
          "days": 31,
          "mentions": 1121,
          "perDay": 36.2,
          "per1000": 87.1
        },
        {
          "month": "2026-08",
          "days": 31,
          "mentions": 1013,
          "perDay": 32.7,
          "per1000": 85.3
        },
        {
          "month": "2026-09",
          "days": 30,
          "mentions": 795,
          "perDay": 26.5,
          "per1000": 83.7
        },
        {
          "month": "2026-10",
          "days": 22,
          "mentions": 596,
          "perDay": 27.1,
          "per1000": 87.3
        }
      ]
    },
    {
      "slug": "ghk-cu",
      "name": "GHK-Cu",
      "inDataset": true,
      "rank": 4,
      "mentions": 124,
      "perDay": 5.6,
      "per1000": 18.2,
      "prevMentions": 215,
      "prevPerDay": 7.2,
      "prevPer1000": 22.6,
      "paceChangePct": -21,
      "shareChangePct": -20,
      "series": [
        {
          "month": "2026-05",
          "days": 31,
          "mentions": 643,
          "perDay": 20.7,
          "per1000": 38.4
        },
        {
          "month": "2026-06",
          "days": 30,
          "mentions": 486,
          "perDay": 16.2,
          "per1000": 35.7
        },
        {
          "month": "2026-07",
          "days": 31,
          "mentions": 368,
          "perDay": 11.9,
          "per1000": 28.6
        },
        {
          "month": "2026-08",
          "days": 31,
          "mentions": 326,
          "perDay": 10.5,
          "per1000": 27.4
        },
        {
          "month": "2026-09",
          "days": 30,
          "mentions": 215,
          "perDay": 7.2,
          "per1000": 22.6
        },
        {
          "month": "2026-10",
          "days": 22,
          "mentions": 124,
          "perDay": 5.6,
          "per1000": 18.2
        }
      ]
    },
    {
      "slug": "bpc-157",
      "name": "BPC-157",
      "inDataset": true,
      "rank": 5,
      "mentions": 101,
      "perDay": 4.6,
      "per1000": 14.8,
      "prevMentions": 183,
      "prevPerDay": 6.1,
      "prevPer1000": 19.3,
      "paceChangePct": -25,
      "shareChangePct": -23,
      "series": [
        {
          "month": "2026-05",
          "days": 31,
          "mentions": 338,
          "perDay": 10.9,
          "per1000": 20.2
        },
        {
          "month": "2026-06",
          "days": 30,
          "mentions": 285,
          "perDay": 9.5,
          "per1000": 20.9
        },
        {
          "month": "2026-07",
          "days": 31,
          "mentions": 242,
          "perDay": 7.8,
          "per1000": 18.8
        },
        {
          "month": "2026-08",
          "days": 31,
          "mentions": 233,
          "perDay": 7.5,
          "per1000": 19.6
        },
        {
          "month": "2026-09",
          "days": 30,
          "mentions": 183,
          "perDay": 6.1,
          "per1000": 19.3
        },
        {
          "month": "2026-10",
          "days": 22,
          "mentions": 101,
          "perDay": 4.6,
          "per1000": 14.8
        }
      ]
    },
    {
      "slug": "tesamorelin",
      "name": "Tesamorelin",
      "inDataset": true,
      "rank": 6,
      "mentions": 78,
      "perDay": 3.5,
      "per1000": 11.4,
      "prevMentions": 177,
      "prevPerDay": 5.9,
      "prevPer1000": 18.6,
      "paceChangePct": -40,
      "shareChangePct": -39,
      "series": [
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          "month": "2026-05",
          "days": 31,
          "mentions": 338,
          "perDay": 10.9,
          "per1000": 20.2
        },
        {
          "month": "2026-06",
          "days": 30,
          "mentions": 225,
          "perDay": 7.5,
          "per1000": 16.5
        },
        {
          "month": "2026-07",
          "days": 31,
          "mentions": 234,
          "perDay": 7.5,
          "per1000": 18.2
        },
        {
          "month": "2026-08",
          "days": 31,
          "mentions": 208,
          "perDay": 6.7,
          "per1000": 17.5
        },
        {
          "month": "2026-09",
          "days": 30,
          "mentions": 177,
          "perDay": 5.9,
          "per1000": 18.6
        },
        {
          "month": "2026-10",
          "days": 22,
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          "perDay": 3.5,
          "per1000": 11.4
        }
      ]
    },
    {
      "slug": "cjc-1295",
      "name": "CJC-1295",
      "inDataset": true,
      "rank": 7,
      "mentions": 76,
      "perDay": 3.5,
      "per1000": 11.1,
      "prevMentions": 158,
      "prevPerDay": 5.3,
      "prevPer1000": 16.6,
      "paceChangePct": -34,
      "shareChangePct": -33,
      "series": [
        {
          "month": "2026-05",
          "days": 31,
          "mentions": 302,
          "perDay": 9.7,
          "per1000": 18
        },
        {
          "month": "2026-06",
          "days": 30,
          "mentions": 205,
          "perDay": 6.8,
          "per1000": 15.1
        },
        {
          "month": "2026-07",
          "days": 31,
          "mentions": 182,
          "perDay": 5.9,
          "per1000": 14.1
        },
        {
          "month": "2026-08",
          "days": 31,
          "mentions": 167,
          "perDay": 5.4,
          "per1000": 14.1
        },
        {
          "month": "2026-09",
          "days": 30,
          "mentions": 158,
          "perDay": 5.3,
          "per1000": 16.6
        },
        {
          "month": "2026-10",
          "days": 22,
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          "perDay": 3.5,
          "per1000": 11.1
        }
      ]
    },
    {
      "slug": "mots-c",
      "name": "MOTS-c",
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      "rank": 8,
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      "perDay": 3.3,
      "per1000": 10.7,
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      "prevPerDay": 4.4,
      "prevPer1000": 14,
      "paceChangePct": -25,
      "shareChangePct": -24,
      "series": [
        {
          "month": "2026-05",
          "days": 31,
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          "perDay": 9,
          "per1000": 16.7
        },
        {
          "month": "2026-06",
          "days": 30,
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          "perDay": 7.1,
          "per1000": 15.6
        },
        {
          "month": "2026-07",
          "days": 31,
          "mentions": 229,
          "perDay": 7.4,
          "per1000": 17.8
        },
        {
          "month": "2026-08",
          "days": 31,
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          "perDay": 5.6,
          "per1000": 14.6
        },
        {
          "month": "2026-09",
          "days": 30,
          "mentions": 133,
          "perDay": 4.4,
          "per1000": 14
        },
        {
          "month": "2026-10",
          "days": 22,
          "mentions": 73,
          "perDay": 3.3,
          "per1000": 10.7
        }
      ]
    },
    {
      "slug": "nad-plus",
      "name": "NAD+",
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      "rank": 9,
      "mentions": 72,
      "perDay": 3.3,
      "per1000": 10.5,
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      "prevPer1000": 12.9,
      "paceChangePct": -20,
      "shareChangePct": -19,
      "series": [
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          "month": "2026-05",
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          "perDay": 6.8,
          "per1000": 12.6
        },
        {
          "month": "2026-06",
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          "per1000": 10.5
        },
        {
          "month": "2026-07",
          "days": 31,
          "mentions": 128,
          "perDay": 4.1,
          "per1000": 9.9
        },
        {
          "month": "2026-08",
          "days": 31,
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          "perDay": 3.9,
          "per1000": 10.2
        },
        {
          "month": "2026-09",
          "days": 30,
          "mentions": 123,
          "perDay": 4.1,
          "per1000": 12.9
        },
        {
          "month": "2026-10",
          "days": 22,
          "mentions": 72,
          "perDay": 3.3,
          "per1000": 10.5
        }
      ]
    },
    {
      "slug": "klow",
      "name": "KLOW",
      "inDataset": true,
      "rank": 10,
      "mentions": 66,
      "perDay": 3,
      "per1000": 9.7,
      "prevMentions": 126,
      "prevPerDay": 4.2,
      "prevPer1000": 13.3,
      "paceChangePct": -29,
      "shareChangePct": -27,
      "series": [
        {
          "month": "2026-05",
          "days": 31,
          "mentions": 199,
          "perDay": 6.4,
          "per1000": 11.9
        },
        {
          "month": "2026-06",
          "days": 30,
          "mentions": 168,
          "perDay": 5.6,
          "per1000": 12.3
        },
        {
          "month": "2026-07",
          "days": 31,
          "mentions": 132,
          "perDay": 4.3,
          "per1000": 10.3
        },
        {
          "month": "2026-08",
          "days": 31,
          "mentions": 118,
          "perDay": 3.8,
          "per1000": 9.9
        },
        {
          "month": "2026-09",
          "days": 30,
          "mentions": 126,
          "perDay": 4.2,
          "per1000": 13.3
        },
        {
          "month": "2026-10",
          "days": 22,
          "mentions": 66,
          "perDay": 3,
          "per1000": 9.7
        }
      ]
    },
    {
      "slug": "tb-500",
      "name": "TB-500",
      "inDataset": true,
      "rank": 11,
      "mentions": 53,
      "perDay": 2.4,
      "per1000": 7.8,
      "prevMentions": 93,
      "prevPerDay": 3.1,
      "prevPer1000": 9.8,
      "paceChangePct": -22,
      "shareChangePct": -21,
      "series": [
        {
          "month": "2026-05",
          "days": 31,
          "mentions": 189,
          "perDay": 6.1,
          "per1000": 11.3
        },
        {
          "month": "2026-06",
          "days": 30,
          "mentions": 143,
          "perDay": 4.8,
          "per1000": 10.5
        },
        {
          "month": "2026-07",
          "days": 31,
          "mentions": 138,
          "perDay": 4.5,
          "per1000": 10.7
        },
        {
          "month": "2026-08",
          "days": 31,
          "mentions": 125,
          "perDay": 4,
          "per1000": 10.5
        },
        {
          "month": "2026-09",
          "days": 30,
          "mentions": 93,
          "perDay": 3.1,
          "per1000": 9.8
        },
        {
          "month": "2026-10",
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          "perDay": 2.4,
          "per1000": 7.8
        }
      ]
    },
    {
      "slug": "semax",
      "name": "Semax",
      "inDataset": true,
      "rank": 12,
      "mentions": 51,
      "perDay": 2.3,
      "per1000": 7.5,
      "prevMentions": 76,
      "prevPerDay": 2.5,
      "prevPer1000": 8,
      "paceChangePct": -8,
      "shareChangePct": -7,
      "series": [
        {
          "month": "2026-05",
          "days": 31,
          "mentions": 154,
          "perDay": 5,
          "per1000": 9.2
        },
        {
          "month": "2026-06",
          "days": 30,
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          "perDay": 3.6,
          "per1000": 8
        },
        {
          "month": "2026-07",
          "days": 31,
          "mentions": 130,
          "perDay": 4.2,
          "per1000": 10.1
        },
        {
          "month": "2026-08",
          "days": 31,
          "mentions": 98,
          "perDay": 3.2,
          "per1000": 8.2
        },
        {
          "month": "2026-09",
          "days": 30,
          "mentions": 76,
          "perDay": 2.5,
          "per1000": 8
        },
        {
          "month": "2026-10",
          "days": 22,
          "mentions": 51,
          "perDay": 2.3,
          "per1000": 7.5
        }
      ]
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          "prevSharePct": 22.9,
          "changePts": 2.3
        }
      ]
    }
  ],
  "newCompounds": [
    {
      "slug": "eloralintide",
      "name": "Eloralintide",
      "inDataset": true,
      "mentions": 11,
      "perDay": 0.5,
      "priorPerDay": 0.24,
      "firstSeen": "2025-11"
    }
  ],
  "questions": {
    "total": 1585,
    "prevTotal": 2180,
    "topics": [
      {
        "id": "other",
        "label": "Other questions",
        "mentions": 500,
        "sharePct": 31.5,
        "prevMentions": 615,
        "prevSharePct": 28.2,
        "changePts": 3.3
      },
      {
        "id": "dosing",
        "label": "Dosing",
        "mentions": 258,
        "sharePct": 16.3,
        "prevMentions": 369,
        "prevSharePct": 16.9,
        "changePts": -0.6
      },
      {
        "id": "side_effects",
        "label": "Side effects",
        "mentions": 194,
        "sharePct": 12.2,
        "prevMentions": 245,
        "prevSharePct": 11.2,
        "changePts": 1
      },
      {
        "id": "results",
        "label": "Results and plateaus",
        "mentions": 168,
        "sharePct": 10.6,
        "prevMentions": 226,
        "prevSharePct": 10.4,
        "changePts": 0.2
      },
      {
        "id": "sourcing",
        "label": "Buying and lab testing",
        "mentions": 113,
        "sharePct": 7.1,
        "prevMentions": 149,
        "prevSharePct": 6.8,
        "changePts": 0.3
      },
      {
        "id": "injecting",
        "label": "Injecting",
        "mentions": 103,
        "sharePct": 6.5,
        "prevMentions": 178,
        "prevSharePct": 8.2,
        "changePts": -1.7
      },
      {
        "id": "timing",
        "label": "Timing and schedule",
        "mentions": 99,
        "sharePct": 6.2,
        "prevMentions": 136,
        "prevSharePct": 6.2,
        "changePts": 0
      },
      {
        "id": "stacking",
        "label": "Stacking and combining",
        "mentions": 75,
        "sharePct": 4.7,
        "prevMentions": 119,
        "prevSharePct": 5.5,
        "changePts": -0.8
      },
      {
        "id": "mixing",
        "label": "Mixing and reconstitution",
        "mentions": 46,
        "sharePct": 2.9,
        "prevMentions": 97,
        "prevSharePct": 4.4,
        "changePts": -1.5
      },
      {
        "id": "storage",
        "label": "Storage and travel",
        "mentions": 29,
        "sharePct": 1.8,
        "prevMentions": 46,
        "prevSharePct": 2.1,
        "changePts": -0.3
      }
    ],
    "byCompound": [
      {
        "slug": "retatrutide",
        "name": "Retatrutide",
        "questions": 733,
        "topTopic": "dosing",
        "topTopicLabel": "Dosing"
      },
      {
        "slug": "tirzepatide",
        "name": "Tirzepatide",
        "questions": 596,
        "topTopic": "dosing",
        "topTopicLabel": "Dosing"
      },
      {
        "slug": "semaglutide",
        "name": "Semaglutide",
        "questions": 173,
        "topTopic": "dosing",
        "topTopicLabel": "Dosing"
      },
      {
        "slug": "ghk-cu",
        "name": "GHK-Cu",
        "questions": 45,
        "topTopic": "mixing",
        "topTopicLabel": "Mixing and reconstitution"
      },
      {
        "slug": "bpc-157",
        "name": "BPC-157",
        "questions": 42,
        "topTopic": "stacking",
        "topTopicLabel": "Stacking and combining"
      },
      {
        "slug": "nad-plus",
        "name": "NAD+",
        "questions": 32,
        "topTopic": "injecting",
        "topTopicLabel": "Injecting"
      },
      {
        "slug": "cjc-1295",
        "name": "CJC-1295",
        "questions": 24,
        "topTopic": "stacking",
        "topTopicLabel": "Stacking and combining"
      },
      {
        "slug": "tesamorelin",
        "name": "Tesamorelin",
        "questions": 22,
        "topTopic": "stacking",
        "topTopicLabel": "Stacking and combining"
      },
      {
        "slug": "klow",
        "name": "KLOW",
        "questions": 21,
        "topTopic": "stacking",
        "topTopicLabel": "Stacking and combining"
      },
      {
        "slug": "mots-c",
        "name": "MOTS-c",
        "questions": 18,
        "topTopic": "stacking",
        "topTopicLabel": "Stacking and combining"
      }
    ],
    "examples": [
      {
        "topic": "dosing",
        "title": "Retatrutide beginners - did anyone start at 1 mg instead of 2 mg?",
        "url": "https://www.reddit.com/comments/1x3qctk",
        "subreddit": "Retatrutide",
        "comments": 261,
        "slug": "retatrutide"
      },
      {
        "topic": "dosing",
        "title": "Wrong dosage, is this a problem?",
        "url": "https://www.reddit.com/comments/1xa72id",
        "subreddit": "tirzepatidecompound",
        "comments": 81,
        "slug": "tirzepatide"
      },
      {
        "topic": "side_effects",
        "title": "Those on reta, what has been your positive side effects?",
        "url": "https://www.reddit.com/comments/1xcafy7",
        "subreddit": "Retatrutide",
        "comments": 124,
        "slug": "retatrutide"
      },
      {
        "topic": "side_effects",
        "title": "Are you all not nauseous all the time?",
        "url": "https://www.reddit.com/comments/1x7omkl",
        "subreddit": "tirzepatidecompound",
        "comments": 86,
        "slug": "tirzepatide"
      },
      {
        "topic": "results",
        "title": "How do you keep up with clothes during a major weight loss? Nothing fits anymore.",
        "url": "https://www.reddit.com/comments/1wvynsk",
        "subreddit": "tirzepatidecompound",
        "comments": 130,
        "slug": "tirzepatide"
      },
      {
        "topic": "results",
        "title": "What's been the hardest physical change to deal with while losing weight?",
        "url": "https://www.reddit.com/comments/1x964jf",
        "subreddit": "Semaglutide",
        "comments": 127,
        "slug": "semaglutide"
      },
      {
        "topic": "injecting",
        "title": "Anyone injecting into ‘love handles’ on hips?",
        "url": "https://www.reddit.com/comments/1xa7rhg",
        "subreddit": "tirzepatidecompound",
        "comments": 153,
        "slug": "tirzepatide"
      },
      {
        "topic": "injecting",
        "title": "Best time of day to inject?",
        "url": "https://www.reddit.com/comments/1x4hbtd",
        "subreddit": "tirzepatidecompound",
        "comments": 70,
        "slug": "tirzepatide"
      },
      {
        "topic": "timing",
        "title": "What to do when even maintenance feels like a deficit?",
        "url": "https://www.reddit.com/comments/1x4efg5",
        "subreddit": "Biohackers",
        "comments": 363,
        "slug": "semaglutide"
      },
      {
        "topic": "timing",
        "title": "What do you experience when you eat a big meal?",
        "url": "https://www.reddit.com/comments/1x9fgzy",
        "subreddit": "tirzepatidecompound",
        "comments": 59,
        "slug": "tirzepatide"
      }
    ]
  },
  "downloads": [
    {
      "id": "mentions",
      "file": "mentions.csv",
      "title": "Mentions per compound and month",
      "rows": 414,
      "columns": [
        "slug",
        "compound",
        "in_dataset",
        "month",
        "days_covered",
        "posts_mentioning",
        "per_day",
        "per_1000_posts"
      ]
    },
    {
      "id": "movers",
      "file": "movers.csv",
      "title": "Fastest-rising and cooling compounds (share of posts vs last month)",
      "rows": 6,
      "columns": [
        "direction",
        "slug",
        "compound",
        "posts_mentioning",
        "prev_posts_mentioning",
        "per_1000_posts",
        "prev_per_1000_posts",
        "share_change_pct",
        "pace_change_pct"
      ]
    },
    {
      "id": "side-effects",
      "file": "side-effects.csv",
      "title": "Side effects discussed per compound and month (share of single-compound posts with text)",
      "rows": 144,
      "columns": [
        "slug",
        "compound",
        "effect_id",
        "effect",
        "month",
        "posts_mentioning",
        "posts_base",
        "share_pct"
      ]
    },
    {
      "id": "doses",
      "file": "doses.csv",
      "title": "Dose amounts named per compound, this month and last month",
      "rows": 27,
      "columns": [
        "slug",
        "compound",
        "unit",
        "amount",
        "label",
        "mentions",
        "share_pct",
        "prev_mentions",
        "prev_share_pct",
        "change_pts"
      ]
    },
    {
      "id": "new-compounds",
      "file": "new-compounds.csv",
      "title": "Compounds new or newly busy this month",
      "rows": 1,
      "columns": [
        "slug",
        "compound",
        "in_dataset",
        "posts_mentioning",
        "per_day",
        "prior_per_day",
        "first_seen"
      ]
    },
    {
      "id": "questions",
      "file": "questions.csv",
      "title": "Question posts by topic, this month and last month",
      "rows": 10,
      "columns": [
        "topic_id",
        "topic",
        "questions",
        "share_pct",
        "prev_questions",
        "prev_share_pct",
        "change_pts"
      ]
    }
  ],
  "method": {
    "version": "2026-10-24",
    "notes": [
      "Source: public posts (not comments) in the tracked subreddits, stored by our community job from the Arctic Shift Reddit archive. Authors are never stored.",
      "A mention is one post that names the compound, or any post in that compound's own subreddit. Per day divides by the days of the month the archive covers; per 1,000 posts divides by all posts in the tracked subreddits that month.",
      "Side effects and dose amounts are read only from posts about a single compound that have body text. A side effect counts once per post, and not when negated (\"no nausea\"). Shares are of posts that bring an effect up, never how often it happens.",
      "Dose amounts are single mg or mcg amounts parsed in code. Ranges, vial and kit sizes, concentrations, amounts next to non-peptides and amounts far outside every sourced dose in our dataset are skipped.",
      "Questions are posts whose title asks one, sorted into topics by fixed word lists. Example threads are cited by their own titles and links.",
      "Every number is computed in code. A model writes the captions from those numbers, and a caption with any number not in the computed values is replaced by a code-written one."
    ]
  },
  "license": {
    "name": "CC BY 4.0",
    "url": "https://creativecommons.org/licenses/by/4.0/",
    "attribution": "TruePeptideSource, State of Peptides: October 2026"
  }
}