Forum convention
Who: Forum protocols compiled in a 2026 peer-reviewed review
Timing: Bedtime, on an empty stomach.
Some human trialsFormerly approved as Geref
Sermorelin dosage
Also known as: Sermorelin acetate · GRF 1-29 NH2 · GHRH (1-29) · Geref
Updated 20 sources
Every Sermorelin protocol on file, 11 in all, labelled by where each number came from.
Sermorelin dosage by goal
Grouped by goal. Each protocol shows the amount, how often, cycle and rest as the source states them, with every titration step.
Injected11
Self-logged doses
Who: 26 repeat reporters on a self-logging tracker
Standard nightly
Timing: 3 or more hours after the last meal.
Advanced nightly
Timing: 3 or more hours after the last meal.
12-week arc with IGF-1 check
Timing: 30 to 60 minutes before sleep, fasted 90 minutes or more. 200 mcg in weeks 1 to 2, IGF-1 check at weeks 6 to 8, then adjust by 50 to 100 mcg.
Lower start for smaller adults and most women
Who: Smaller adults and most women, per one guide
Timing: 30 to 60 minutes before sleep, fasted.
Stacked with ipamorelin
Performance block
Timing: Fasting matters less than with ipamorelin, but avoid high-carb meals within 2 hours.
Anti-aging course
Educational chart
Timing: Titrate up gradually.
Clinic regimen with GHRP-2 and GHRP-6
Who: Hypogonadal men in a men's health clinic record review, alongside testosterone therapy
Doses shown are what sources report, labelled by origin. Not medical advice.
Community-reported amounts
The Sermorelin amounts people mention most on Reddit, by goal. Counts, not recommendations.
| Goal | Most reported amounts (mentions) |
|---|---|
| Goal not stated | 0.2 mg (3), 100 mcg (3), 200 mcg (3), 300 mcg (3) |
| Weight loss | 300 mcg (5), 750 mcg (2) |
| Muscle growth | 300 mcg (2) |
From 673 Reddit posts and comments, last mined Oct 23, 2026.
Sermorelin dosage chart by vial size
Units to draw for the doses sources cite most, at every vial size and water volume.
| Water | Strength | 200 mcgdose, units | 300 mcgdose, units | 500 mcgdose, units |
|---|---|---|---|---|
| 5 mg vial | ||||
| 3 mLCompetitor guide | 1.667 mg/mL | 120.12 mL | 180.18 mL | 300.3 mL |
| 6 mg vial | ||||
| 2 mLCompetitor guide | 3 mg/mL | 6.70.067 mL | 100.1 mL | 16.70.167 mL |
| 3 mLCompetitor guide | 2 mg/mL | 100.1 mL | 150.15 mL | 250.25 mL |
| 6 mLCompetitor guide | 1 mg/mL | 200.2 mL | 300.3 mL | 500.5 mL |
| 10 mg vial | ||||
| 2 mLCompetitor guide | 5 mg/mL | 40.04 mL | 60.06 mL | 100.1 mL |
Units are on a U-100 insulin syringe (100 units = 1 mL). U-50 and U-30 barrels read the same units.Water volumes from
Doses shown are what sources report, labelled by origin. Not medical advice.
Calculate with this peptideYour vial, your water, your dose: Sermorelin in syringe units, with the math shown.Mixing Sermorelin
Diluent: Bacteriostatic water
Water volumes sources use: 2 mL, 3 mL, 6 mL
2 mL in a 6 mg vial is the most common choice. One guide mixes any vial to 1 mg/mL so the math stays simple. The old Geref product came as a 0.05 mg ampule and 0.5 and 1 mg vials.
Sermorelin dosage questions
How much sermorelin per day?
200 to 300 mcg nightly is the clear center. Adult guides range from 100 to 500 mcg.
What is the sermorelin dose in units or mL?
It depends on how much water you add. A 6 mg vial with 2 mL gives 3 mg/mL. Use the calculator to turn your dose into mL and syringe units.
What dose do women use?
One guide starts most women and smaller adults lower, at 100 to 150 mcg. Another frames it by weight at about 1 to 2 mcg/kg.
What dose do men use?
The same 200 to 300 mcg nightly center. In a clinic record review, men on testosterone therapy took 100 mcg 3 times a day alongside GHRP-2 and GHRP-6.
What dose did the approved drug use?
30 mcg/kg nightly under the skin for children with GH deficiency, and 1 mcg/kg IV as a diagnostic test. That pediatric dose is far higher per kg than adult clinic doses, so guides that anchor on it are mixing populations.
What dose for muscle growth?
Guides give 300 to 500 mcg. No trial supports a muscle effect.
Sources for these doses
9 sources, each checked by date. Record updated Oct 23, 2026. Numbers are restated in our own words and labelled by where they came from.
Clinical study1
- GHS treatment in hypogonadal men raises IGF-1 (Sigalos 2017)PubMed · checked Oct 23, 2026
Competitor guide6
- Sermorelin dosage guideBodyHackGuide · checked Oct 23, 2026
- Sermorelin dosage chartPeptidesExplorer · checked Oct 23, 2026
- SermorelinPeptidesExplorer · checked Oct 23, 2026
- Sermorelin dosage guidePeptideDeck · checked Oct 23, 2026
Community-reported2
- Performance-enhancing peptides modulating GH-IGF1 axis (Dominikowski 2026)PMC · checked Oct 23, 2026
- Sermorelin (self-logged doses)PeptIQ · checked Oct 23, 2026
Back to the full Sermorelin page for side effects, storage, stacks and legal status.