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Animal data onlyNot FDA approved

TB-500 dosage

Also known as: TB500 · TB 500 · Thymosin beta-4 fragment · Ac-LKKTETQ · TB-500 acetate

Updated 40 sources

Every TB-500 protocol on file, 19 in all, labelled by where each number came from.

Calculate with TB-500TB-500 overview

TB-500 dosage by goal

Grouped by goal. Each protocol shows the amount, how often, cycle and rest as the source states them, with every titration step.

Loading phase2

Loading phase (standard)

Amount
2 to 2.5 mg
How often
Twice weekly (4 to 5 mg a week)
Route
SubQ, vial (powder)
Cycle
4 to 6 weeks, then maintenance

Timing: Usually 72 hours apart, such as Monday and Thursday. SubQ in the belly or flank; the site does not matter, but not into a sore tendon or joint. No fasting needed. Evening dosing helps people sleep through fatigue.

Loading phase (intramuscular)

Amount
2 to 2.5 mg
How often
Twice weekly
Route
IM, vial (powder)

Timing: Some use IM into the outer thigh or the side of the glute instead of subQ.

Acute injury2

Acute injury

Amount
2 to 2.5 mg
How often
Every 2 to 3 days for 2 weeks, then weekly to week 8
Route
SubQ, vial (powder)
Cycle
8 weeks

Acute injury, shorter

Amount
2 mg
How often
Every 3 to 4 days
Route
SubQ, vial (powder)
Cycle
3 weeks

Other protocols: injected15

Maintenance phase

Amount
2 to 2.5 mg
How often
Once weekly
Route
SubQ, vial (powder)
Cycle
4 to 8 weeks after loading
Rest
2 to 8 weeks off, depending on the guide

Loading by experience tier

Amount
2 to 5 mg
How often
Twice weekly: 2 mg beginner, 2.5 mg standard, 5 mg advanced
Route
SubQ, vial (powder)
Cycle
4 weeks, then 2 to 2.5 mg weekly
Rest
2 to 4 weeks off

Higher loading

Amount
2 to 5 mg
How often
Twice weekly
Route
SubQ, vial (powder)
Cycle
4 to 8 weeks

Who: Some guides start at 5 mg twice weekly for 2 to 4 weeks, then halve to about 2.5 mg weekly.

Conservative to high loading

Amount
2 to 3 mg
How often
Twice weekly: 2 mg conservative, 2.5 mg standard, 3 mg high
Route
SubQ, vial (powder)
Cycle
10 to 12 weeks in total
Rest
4 weeks off

Long-interval maintenance

Amount
2 to 2.5 mg
How often
Every 10 days; some stretch to 2 mg every 2 weeks
Route
SubQ, vial (powder)

Daily ladder (outlier)

Amount
500 to 1,000 mcg
How often
Once daily, stepping 500, 600, 750 then 1,000 mcg (about 5 mg a week on average)
Route
SubQ, vial (powder)
Cycle
12 weeks

Daily load then half (outlier)

Amount
1 to 2 mg
How often
2 mg daily for 15 days, then 1 mg daily
Route
SubQ, vial (powder)

Daily inside a BPC-157 stack (outlier)

Amount
2.5 mg
How often
Once daily
Route
SubQ, vial (powder)
Cycle
2 weeks

Timing: Taper TB-500 before BPC-157 when ending the stack.

Low daily (outlier)

Amount
750 mcg
How often
Once daily
Route
SubQ, vial (powder)
Cycle
3 months

Every other day (outlier)

Amount
3 mg
How often
Every other day
Route
SubQ, vial (powder)

Microdose like BPC-157 (outlier)

Amount
500 to 1,000 mcg
How often
Daily
Route
SubQ, vial (powder)

Dog-scaled weekly total

Amount
0.084 mg/kg
How often
Weekly total
Route
SubQ, vial (powder)

Note: Scaled from dog dosing; about 7.7 mg a week at 91 kg.

Forum high loading

Amount
5 mg
How often
5 mg shots, about 10 mg a week (some go to 20 mg) for 4 to 6 weeks, then 5 mg weekly
Route
SubQ, vial (powder)
Cycle
4 to 6 weeks of loading

Forum short loading

Amount
2.5 mg
How often
Twice weekly for 2 weeks, then weekly
Route
SubQ, vial (powder)

Who: One forum user, who said he noticed a difference after the second shot.

Forum long run

Amount
2.5 mg
How often
Every third day
Route
SubQ, vial (powder)
Cycle
About 4 months

Who: One 2014 log for elbow tendinitis. The user said it did nothing and was expensive.

Doses shown are what sources report, labelled by origin. Not medical advice.

Community-reported amounts

The TB-500 amounts people mention most on Reddit, by goal. Counts, not recommendations.
TB-500 amounts reported on Reddit, by goal, with mention counts
GoalMost reported amounts (mentions)
Injury recovery500 mcg (43), 250 mcg (19), 1 mg (18), 2 mg (15)
Goal not stated500 mcg (18), 250 mcg (10), 2.5 mg (8), 0.5 mg (4)
General use1 mg (2)
From 900 Reddit posts and comments, last mined Oct 24, 2026.

TB-500 dosage chart by vial size

Units to draw for the doses sources cite most, at every vial size and water volume.
TB-500: concentration and U-100 syringe units for each vial size and water volume
WaterStrength2 mgdose, units2.5 mgdose, units5 mgdose, units
2 mg vial
1 mLCompetitor guide2 mg/mL1001 mL1251.25 mL2 draws2502.5 mL3 draws
5 mg vial
1 mLCompetitor guide5 mg/mL400.4 mL500.5 mL1001 mL
2 mLCompetitor guide2.5 mg/mL800.8 mL1001 mL2002 mL2 draws
10 mg vial
2 mLCompetitor guide5 mg/mL400.4 mL500.5 mL1001 mL
3 mLCompetitor guide3.333 mg/mL600.6 mL750.75 mL1501.5 mL2 draws
Units are on a U-100 insulin syringe (100 units = 1 mL). U-50 and U-30 barrels read the same units.Water volumes from

Doses shown are what sources report, labelled by origin. Not medical advice.

Calculate with this peptideYour vial, your water, your dose: TB-500 in syringe units, with the math shown.

Mixing TB-500

Diluent: Bacteriostatic water

Water volumes sources use: 1 mL, 2 mL, 3 mL

TB-500 doses are large by volume. One guide suggests picking the water so a dose lands between 20 and 60 units. Draws of 0.5 to 1 mL can be split across two sites.

If you miss a dose

Take it within a day, or skip it.

TB-500 dosage questions

How much and how often?

The common pattern is 2 to 2.5 mg twice weekly for 4 to 6 weeks, then 2 to 2.5 mg once a week. That is 4 to 5 mg a week while loading. Forums often run much higher, 10 to 20 mg a week.

How many units is 2.5 mg?

With 10 mg in 2 mL, 2.5 mg is 50 units on a U-100 syringe. Use the calculator for other mixes.

What doses do people actually log?

In one tracking app with 103 TB-500 users, the most common entry was 2 to 3 mg per injection (72 logs), then 3 to 5 mg (45), 5 mg or more (25), plus a micro-dose group at 0.2 to 0.6 mg (54). 38% rated their experience favorable and 62% mixed.

Should I dose by body weight?

Usually not. One site uses a weight table with 2 to 3 mg loading doses by bracket, and one dog-scaled figure gives 0.084 mg/kg a week.

What if I miss a dose?

Take it within a day or skip it.

Sources for these doses

24 sources, each checked by date. Record updated Oct 23, 2026. Numbers are restated in our own words and labelled by where they came from.

Vendor guide1

  1. TB-500 10 mg product pageVendor product page · checked Oct 23, 2026

Competitor guide20

  1. TB-500 dosage chartpeptidedeck.com · checked Oct 23, 2026
  2. TB-500 protocolpeptidedosingprotocols.com · checked Oct 23, 2026
  3. TB-500 profilepathtopeptides.com · checked Oct 23, 2026
  4. TB-500 dosage guidepeptidedeck.com · checked Oct 23, 2026

Community-reported3

  1. BPC-157 and how to stackelitefitness.com forum · checked Oct 23, 2026
  2. BPC-157 for sore jointselitefitness.com forum · checked Oct 23, 2026
  3. Elcsum's 6-month peptide and SARM logelitefitness.com forum · checked Oct 23, 2026

Back to the full TB-500 page for side effects, storage, stacks and legal status.