Also known as: Acetyl octapeptide-3 · Acetyl glutamyl heptapeptide-3 · Snap 8 · SNAP8 · Ac-EEMQRRAD-NH2
Updated 27 sources
Every SNAP-8 protocol on file, 7 in all, labelled by where each number came from. 2 have titration steps, each step is worked out in U-100 units for a 10 mg vial + 5 mL water.
Who: The strength of pure SNAP-8 in a finished product, as worked out from the developer's range
Note: This is pure peptide. 0.005% equals 50 ppm. Labels that say 3 to 10% mean the dilute supplied solution, not the peptide itself.
Who: Products and DIY serums made with the supplied cosmetic solution
Note: The percent is of the supplied solution, which holds 0.05% peptide. Added to formulas below 40 C at cool-down.
Who: One guide's tiers for the supplied solution: 1 to 3% basic, 3 to 5% standard, 5 to 10% intensive
Note: Percent of the supplied solution, not pure peptide. The same guide says above 10% gives diminishing returns.
Who: Users making or buying serums, as collected from r/DIYBeauty and r/SkincareAddiction
Note: Percent of the supplied solution. DIY formulators in the same collection add 5 to 10% to their own serum base.
Who: One guide doses the cream by peptide mass rather than percent: 200 mcg for cosmetic use, 250 mcg for what it calls neuromodulation
Note: An outlier format. No study doses SNAP-8 this way.
Who: One guide's facial protocol. No study has tested injected SNAP-8.
| When | Dose | U-100 units (10 mg vial + 5 mL water) |
|---|---|---|
| Weeks 1 to 4 | 50 mcg | 2.5 units · 0.025 mL |
| Weeks 5 to 12 | 100 mcg | 5 units · 0.05 mL |
Note: Per site, from a 10 mg vial in 5 mL (2 mg/mL): 2.5 units for 50 mcg, 5 units for 100 mcg. Other guides refuse to give any injection dose, and r/Peptides users warn that cosmetic-grade powder is not sterile.
Who: One calculator site's reference protocol, with no study cited
| When | Dose | U-100 units (10 mg vial + 5 mL water) |
|---|---|---|
| Weeks 1 to 4 | 330 mcg | 16.5 units · 0.165 mL |
| Weeks 5 to 8 | 500 mcg | 25 units · 0.25 mL |
| Weeks 9 to 12 | 1,000 mcg | 50 units · 0.5 mL |
Note: Weeks 1-4 at 330 mcg, 5-8 at 500 mcg, 9-12 at 1 mg, once daily, from a 10 mg vial in 3 mL (about 3.33 mg/mL). The page calls it injectable without naming a route or citing a study. The highest injected figure found.
Doses shown are what sources report, labelled by origin. Not medical advice.
| Water | Strength | 50 mcgdose, units | 100 mcgdose, units | 330 mcgdose, units |
|---|---|---|---|---|
| 10 mg vial | ||||
| 2 mLCommunity-reported | 5 mg/mL | 10.01 mL | 20.02 mL | 6.60.066 mL |
| 3 mLCompetitor guide | 3.333 mg/mL | 1.50.015 mL | 30.03 mL | 9.90.099 mL |
| 5 mLCompetitor guide | 2 mg/mL | 2.50.025 mL | 50.05 mL | 16.50.165 mL |
Doses shown are what sources report, labelled by origin. Not medical advice.
Calculate with this peptideYour vial, your water, your dose: SNAP-8 in syringe units, with the math shown.Diluent: Bacteriostatic water
Water volumes sources use: 2 mL, 3 mL, 5 mL
Add water slowly down the vial wall and swirl, do not shake. For topical use, people mix the dissolved vial into a serum, cream or hyaluronic acid. Cosmetic raw powder is not sterile.
Injection guides use 5 mL (2 mg/mL) or 3 mL (about 3.33 mg/mL). Topical users vary: one r/Biohackers user mixed 10 mg with 2 mL and added it at 10% to a serum.
People do, layered or in one hyaluronic acid serum or cream. There is no controlled data on the pair. Some users keep two separate serums and layer them.
11 sources, each checked by date. Record updated Oct 24, 2026. Numbers are restated in our own words and labelled by where they came from.
Back to the full SNAP-8 page for side effects, storage, stacks and legal status.