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LL-37 vs Thymosin Alpha-1

Updated 13 sources

Key differences

  1. 1LL-37 is innate defence that acts on microbes directly; thymosin alpha-1 works on T cells and adaptive immunity.
  2. 2Ta1 supports adaptive T-cell responses; LL-37 is an antimicrobial peptide of innate defence. Communities stack them.

Side by side

Facts from each record, in the same words as their own pages.
LL-37 and Thymosin Alpha-1 side by side
LL-37Thymosin Alpha-1
Category
  • Immune, Healing & recovery
  • Immune, Longevity
Evidence
  • Limited human data
  • Some human trials
FDA status
  • Not FDA approvedRegulatory
  • Not FDA approvedRegulatory
WADA
  • Not confirmed
  • Not confirmed
Half-life
  • Not measured in humans after injection. One guide cites about 15 to 30 minutes in serum, unsourced.Competitor guide
  • About 30 minutes for the free peptide, cleared by protease breakdown, per one guide; it adds that human data are lacking.Competitor guide
  • About 4 to 6 hours, per one guide, with no source.Competitor guide
  • About 2 hours after an injection under the skin, with peak levels at about 2 hours and no build-up between doses (label).Regulatory
  • About 2 to 3 hours per guides; peak 1 to 2 hours after injection.Competitor guide
Routes
  • Subcutaneous injection, Topical, Other route
  • Subcutaneous injection
Forms
  • Vial (powder), Topical
  • Vial (powder)
Reported doses
  • 25 to 750 mcg (subcutaneous injection)
  • 0.01 to 3.2 mg/mL (topical)
  • 250 mcg (other route)
  • 0.8 to 3.2 mg (subcutaneous injection)
  • 40 mcg/kg (subcutaneous injection)
  • 250 to 500 mcg (subcutaneous injection)
Most cited frequency
  • Daily
  • Twice a week
Vial sizes
  • 5 mg, 10 mgVendor guide
  • 1.6 mg, 5 mg, 10 mg, 20 mgRegulatory
Mixed vial keeps
  • Fridge at 2 to 8 C, dark, never frozen.Competitor guide
  • Zadaxin mixed with its sterile water is single use: inject immediately.Regulatory
Protocols on file
  • 18
  • 19

Doses shown are what sources report, labelled by origin. Not medical advice.

Read each in full

Sources

13 sources, each checked by date. Record updated Oct 24, 2026. Numbers are restated in our own words and labelled by where they came from.

Competitor guide8

  1. LL-37 profilepeptidesexplorer.com · checked Oct 24, 2026
  2. LL-37 research guidepeptidedeck.com · checked Oct 24, 2026
  3. LL-37 dosage guidebodyhackguide.co · checked Oct 24, 2026
  4. Thymosin Alpha-1 (TA1) guidepeptidedosingprotocols.com · checked Oct 24, 2026

Community-reported1

  1. Thymosin Alpha-1 community protocols and reportspeptideprotocolwiki.com, via a competitor guide · checked Oct 24, 2026