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No human trialsNot FDA approvedBlend

CJC-1295 (no DAC) + Ipamorelin side effects

Also known as: CJC-1295/ipamorelin · CJC/Ipa · CJC ipa blend · Mod GRF 1-29 + ipamorelin

Updated 19 sources

8 side effects reported for CJC-1295 (no DAC) + Ipamorelin: 0 from studies and labels, 8 from users and guides. 3 come with the ways people manage them.

Side effects users and guides report

What people post and what dosing guides list. These are reports, not measured rates.

From users and guides8

Community reports, competitor and vendor guides, media.

  • Flushing or warmth after the shot

    Guides report it in the first minutes after injection, mostly in weeks 1 to 2

  • Water retention

    Guides report it in the first 2 to 3 weeks, settling by week 3 to 4. One guide says 10 to 30% of users, with no source for that figure

    How people manage it

    • Keep carbs moderate, per one stack guide.
  • Tingling or numbness in the hands

    Guides read it as a sign GH is running high

    How people manage it

    • One guide cuts ipamorelin by 25 to 50 mcg. With a fixed 1:1 blend you can only lower both together.
    • Some guides check IGF-1 at 6 to 8 weeks and aim for 200 to 300 ng/mL. That is a guide target, not a clinical one.
  • Hunger

    Reported by guides

  • Headache

    Guides report mild headaches in weeks 1 to 2

  • Injection-site irritation or numbness

    Reported by guides

    How people manage it

    • Rotate sites between the lower abdomen and thighs.
  • Vivid dreams

    One guide says 10 to 30% of users, with no source for that figure

  • Carpal-tunnel-like symptoms

    Described as rare, later in a cycle

How much is known

No human trials

No trial of this combination exists, and CJC-1295 no DAC is essentially uncharacterized in humans; its claims are extrapolated from sermorelin. Ipamorelin was well tolerated in a short IV surgery trial. CJC-1295 with DAC showed no serious adverse reactions in healthy adults. In older adults a low GHRP-2 dose amplified the GH response to GHRH, which is the logic behind pairing.

Sources for these side effects

3 sources, each checked by date. Record updated Oct 23, 2026. Numbers are restated in our own words and labelled by where they came from.

Competitor guide3

  1. CJC-1295PeptidesExplorer · checked Oct 23, 2026
  2. CJC-1295 no DAC dosage guideBodyHackGuide · checked Oct 23, 2026
  3. CJC-1295 + ipamorelin stack guidePeptIQ · checked Oct 23, 2026

Back to the full CJC-1295 (no DAC) + Ipamorelin page for dosing, the vial chart and storage.