Epitalon news and clinical trials
Also known as: Epithalon · Epithalone · AEDG · Ala-Glu-Asp-Gly
Updated 86 sources
5 new studies and 1 regulatory action in the last 12 months, newest first: trial registrations and results, PubMed papers, FDA actions and press coverage that name Epitalon. Each line links to the primary source.
October 2026
- StudyPubMedEpitalon and Epithalamin: A Narrative Review of Mechanistic, Preclinical, and Clinical Evidence (opens PubMed)
A narrative review of Epitalon and Epithalamin found that while Epitalon is biologically active in modulating aging markers in preclinical studies, it remains clinically unproven in humans. No adequately powered randomized trial has established therapeutic efficacy.
International journal of molecular sciencesReviewPMID 42884164
May 2026
- StudyPubMedLCP2 mediates SUV39H1-driven cellular senescence-related chemoresistance in natural killer/T-cell lymphoma (opens PubMed)
Researchers identified LCP2 as a biomarker for chemoresistance in natural killer/T-cell lymphoma. Targeting the LCP2-mediated pathway with Epitalon and Chaetocin helped eliminate therapy-induced senescent cells and improved chemotherapy response in vivo.
Cell death & diseasePMID 42209466
April 2026
- StudyPubMedTherapeutic peptides in gerontology: mechanisms and applications for healthy aging (opens PubMed)
New review in Frontiers in aging: Therapeutic peptides in gerontology: mechanisms and applications for healthy aging.
Frontiers in agingReviewPMID 42021992 - RegulatoryFederal RegisterPharmacy Compounding Advisory Committee; Notice of Meeting; Establishment of a Public Docket; Request for Comments-Bulk Drug Substances Nominated for Inclusion on the Section 503A Bulk Drug Substances List (opens Federal Register)
The FDA announced a public advisory committee meeting of the Pharmacy Compounding Advisory Committee to seek input on bulk drug substances nominated for the Section 503A bulk drug substances list.
NoticeFood and Drug Administration2026-07361
January 2026
- StudyPubMedTherapeutic Peptides in Orthopaedics: Applications, Challenges, and Future Directions (opens PubMed)
A review published in the Journal of the American Academy of Orthopaedic Surgeons analyzed the use of therapeutic peptides in orthopaedics. The authors noted that while peptides show promise in preclinical models for tissue regeneration, there is currently a lack of clinical trials.
Journal of the American Academy of Orthopaedic Surgeons. Global research & reviewsReviewPMID 41490200
November 2025
- StudyPubMedCorrection: Epitalon increases telomere length in human cell lines through telomerase upregulation or ALT activity (opens PubMed)
This item is a published correction for a study regarding the effects of Epitalon on telomere length in human cell lines.
BiogerontologyPMID 41240216
Searched as: Epitalon, Epithalon, Epithalone, AEDG, Ala-Glu-Asp-Gly. Summaries are one or two sentences, published only when every number in them appears in the source record. A tracker, not medical advice.