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No human trialsNot FDA approved

N-Acetyl Semax Amidate dosage

Also known as: NA-Semax Amidate · NA-Semax-Amidate · NASA · N-Acetyl-Semax-Amidate Acetate · Ac-Met-Glu-His-Phe-Pro-Gly-Pro-NH2 · Ac-MEHFPGP-NH2

Updated 42 sources

Every N-Acetyl Semax Amidate protocol on file, 9 in all, labelled by where each number came from.

N-Acetyl Semax Amidate dosage by goal

Grouped by goal. Each protocol shows the amount, how often, cycle and rest as the source states them, with every titration step.

Nasal, nasal spray6

Nasal start (daily total, guide)

Amount
600 mcg
How often
Daily total, adjusted to response
Route
Nasal, nasal spray
Cycle
Up to 60 days at 600 mcg a day; no more than 30 days at 900 mcg a day or higher
Rest
A washout as long as the run

Note: Built from plain Semax label doses; the guide says no official dose exists for this variant.

Nasal (daily total, guide)

Amount
200 to 1,200 mcg
How often
Daily total, split into 1 to 2 doses
Route
Nasal, nasal spray
Cycle
14 to 30 days

Note: The guide says the 1 to 2 a day schedule comes from vendor monographs and community use, not measured pharmacokinetics.

Nasal per dose (guide)

Amount
200 to 600 mcg
How often
1 to 2 times a day
Route
Nasal, nasal spray
Cycle
5 days on and 2 off, or 3 to 4 weeks on
Rest
1 week off after a 3 to 4 week run

Timing: Morning and early afternoon; evening doses may be too stimulating

Note: The guide says whether tolerance builds is debated and some use it daily without cycling.

High nasal per dose (guide)

Amount
600 to 1,200 mcg
How often
1 to 2 times a day
Route
Nasal, nasal spray
Cycle
10 to 30 days

Note: The highest guide range we found. The same site lists a molecular weight of 1,007 Da and a wrong sequence, so treat it with care.

Daily nasal (community)

Amount
200 to 600 mcg
How often
Once in the morning, sometimes again in the early afternoon
Route
Nasal, nasal spray

Timing: Morning

Note: Single users on r/Nootropics and r/Peptides. One says too much makes them very sleepy; another felt the same effect at 400 mcg as at 600 mcg.

Spray count, a few days a week (community)

Amount
200 to 400 mcg
How often
A few times a week, 2 sprays, or 4 for a second dose early afternoon
Route
Nasal, nasal spray

Note: On a premixed spray of 100 mcg per spray, one spray per nostril. The user skips daily use because others report fast tolerance.

Injected3

Subcutaneous (daily total, guide)

Amount
500 to 1,000 mcg
How often
Once daily
Route
SubQ, vial (powder)
Cycle
Up to 30 days at 1,000 mcg a day, or up to 60 days at 500 mcg a day
Rest
A rest as long as the run

Note: The guide calls this range anecdotal and says reliable injection data are scarce even for plain Semax.

Subcutaneous per dose (guide)

Amount
200 to 600 mcg
How often
1 to 2 times a day
Route
SubQ, vial (powder)

Note: The guide gives subQ the same range as nasal and notes absorption may differ.

Cautious subcutaneous start (community)

Amount
200 mcg
How often
Once daily
Route
SubQ, vial (powder)

Note: A reply suggesting a lower start than the 300 mcg the poster planned, on the belief that the amidate is much stronger than Semax. No data back that belief.

Doses shown are what sources report, labelled by origin. Not medical advice.

Mixing N-Acetyl Semax Amidate

Diluent: Bacteriostatic water for injection; sterile saline for nasal sprays

No source gives a tested water volume for this peptide. One guide mixes the powder with sterile saline to a 0.1% or 0.3% solution for a spray. Pump volumes vary, so calibrate a homemade spray on a known volume.

N-Acetyl Semax Amidate dosage questions

How much do people take?

Guides run from 200 to 1,200 mcg a day by nasal spray and 500 to 1,000 mcg a day under the skin. Users on Reddit mostly report 200 to 600 mcg in the morning. There is no label or trial dose for this variant.

Should the dose be lower than Semax?

Guides contradict each other. One says cut doses because of the potency claim and start at 100 to 200 mcg. Another starts at 600 mcg a day, the same scale as plain Semax. With no data either way, the one Reddit reply we found on this suggests starting lower, at 200 mcg.

Sources for these doses

13 sources, each checked by date. Record updated Oct 24, 2026. Numbers are restated in our own words and labelled by where they came from.

Competitor guide4

  1. N-Acetyl Semax Amidatepeptides.org · checked Oct 24, 2026
  2. NA-Semax Amidatebodyhackguide.co · checked Oct 24, 2026
  3. NA-Semax Amidatepeptidedeck.com · checked Oct 24, 2026
  4. NA Semax Amidate vs Semaxpeptide-db.com · checked Oct 24, 2026

Community-reported9

  1. r/Peptides: N-Acetyl Semax Amidate (comment)r/Peptides · checked Oct 24, 2026
  2. r/Nootropics: N-Acetyl-Semax-Amidate Acetate (comment)r/Nootropics · checked Oct 24, 2026
  3. r/Nootropics: NA-SEMAX-Amidate experience (comment)r/Nootropics · checked Oct 24, 2026
  4. r/Nootropics: NA-SEMAX-Amidate experience (comment)r/Nootropics · checked Oct 24, 2026

Back to the full N-Acetyl Semax Amidate page for side effects, storage, stacks and legal status.