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Limited human dataNot FDA approved

Selank side effects

Also known as: Selanc · Селанк · TP-7 · TKPRPGP · Thr-Lys-Pro-Arg-Pro-Gly-Pro · Selank acetate · Selank diacetate

Updated 97 sources

10 side effects reported for Selank: 2 from studies and labels, 8 from users and guides. 4 come with the ways people manage them.

Selank overview

Side effects reported in studies and labels

Rates as each trial or label states them. A rate from one trial does not carry over to research-grade vials or other doses.

From trials and regulators2

Clinical studies and regulatory documents.

  • Unpleasant taste

    Listed on the Russian label when drops run into the throat; no rate given

  • Allergic reaction

    Listed on the Russian label for people who are sensitive to the product; no rate given

Side effects users and guides report

What people post and what dosing guides list. These are reports, not measured rates.

From users and guides8

Community reports, competitor and vendor guides, media.

  • Nasal burning, irritation or nosebleeds

    Users tie the burn to bacteriostatic water in DIY sprays. One guide puts nasal irritation at 10 to 15% at higher doses, without a source.

    How people manage it

    • Users switch to sterile saline or sterile water instead of bacteriostatic water in sprays

  • Headache, nausea or flushing

    One r/Peptides user had all three at 200 mcg subQ. One guide says headache is occasional in the first 1 to 3 days; another puts it at 5 to 10%, without a source.

    How people manage it

    • Lower the dose or switch route
    • Test one peptide at a time
    • Some add methylated B vitamins for headache, which is anecdotal
    • Cut caffeine

  • Fatigue

    Called rare by one guide; another puts it at 5 to 8%, without a source

  • Emotional blunting or a flat, zombie feeling

    Reported by a few r/Peptides users, often while on other compounds too

    How people manage it

    • Lower the dose or switch route

  • Hair shedding

    A few anecdotal, confounded reports on r/Peptides; others in the same thread saw no hair loss. No study reports it.

  • Paradoxical anxiety, palpitations or panic

    Rare user reports: paranoia, palpitations and a panic attack followed by a crash. One user had worse anxiety on subQ but relief on nasal.

    How people manage it

    • Switch route; one user found nasal calmer than subQ

  • Vivid dreams

    Single r/Peptides report

  • Injection-site itching or redness

    One subQ user reports it, lasting about 10 minutes

How much is known

Limited human data

Human data come from small Russian trials: 62 patients vs medazepam, 60 vs phenazepam, 70 as an add-on to phenazepam, plus a cytokine study. The label reports 92.8% nasal bioavailability. Animal work covers route comparisons, nose-to-brain delivery and GABA-related genes. A ClinicalTrials.gov search on 2026-10-23 found no registered Selank trials.

Sources for these side effects

17 sources, each checked by date. Record updated Oct 23, 2026. Numbers are restated in our own words and labelled by where they came from.

Regulatory1

  1. Selank instruction for use (Russian label)selank.ru (Peptogen) · checked Oct 23, 2026

Competitor guide2

  1. Selankbodyhackguide.co · checked Oct 23, 2026
  2. Selank dosage guidepeptidesexplorer.com · checked Oct 23, 2026

Community-reported14

  1. Selank Nasal or Sub-Q? (comment)r/Peptides · checked Oct 23, 2026
  2. Reconstituted Selank with BAC water for a nasal spray (comment)r/Peptides · checked Oct 23, 2026
  3. Horrible headaches and nausea from Selankr/Peptides · checked Oct 23, 2026
  4. Horrible headaches and nausea from Selank (comment)r/Peptides · checked Oct 23, 2026

Back to the full Selank page for dosing, the vial chart and storage.