Strong human trialsFDA approved as Egrifta +2

Tesamorelin dosage

Also known as: Tesamorelin acetate · TH9507 · Tesa · Egrifta · Egrifta SV · Egrifta WR

Updated Oct 23, 202629 sources

Every Tesamorelin protocol on file, 11 in all, labelled by where each number came from. 1 have titration steps, each step is worked out in U-100 units for a 2 mg vial + 0.5 mL water.

GH axis

Calculate with Tesamorelin Tesamorelin overview

Tesamorelin dosage by goal

Grouped by goal. Each protocol shows the amount, how often, cycle and rest as the source states them, with every titration step.

Tesamorelin plus ipamorelin 12

Tesamorelin plus ipamorelin 1:1 blend (tesamorelin amount)

Amount: 125 to 1,000 mcg
How often: Once nightly
Route: Subcutaneous injection

Timing: Ipamorelin rises with tesamorelin in a 1:1 blend, which is why blend doses run far below solo doses.

Tesamorelin plus ipamorelin 1:1 blend (total blend)

Amount: 200 mcg
How often: Before bed, 5 days a week
Route: Subcutaneous injection

Other protocols: injected9

Phase 3 trials (original Egrifta)

Amount: 2 mg
How often: Once daily
Route: Subcutaneous injection
Cycle: 26 weeks, with a 26-week extension

Who: Adults with HIV and excess abdominal fat (lipodystrophy)

Egrifta SV label dose

Amount: 1.4 mg
How often: Once daily
Route: Subcutaneous injection

Who: Adults with HIV and lipodystrophy

Timing: Into the abdomen, rotating sites. No time of day is specified. Same exposure as 2 mg of the original formulation.

Egrifta WR label dose

Amount: 1.28 mg
How often: Once daily
Route: Subcutaneous injection

Who: Adults with HIV and lipodystrophy

Timing: Same exposure as 2 mg of the original formulation. Not interchangeable with Egrifta SV.

Forum convention

Amount: 2 mg
How often: Once daily
Route: Subcutaneous injection
Cycle: 8 to 12 weeks

Who: Forum protocols compiled in a 2026 peer-reviewed review

Self-logged doses

Amount: 1 to 2 mg
How often: Per logged entry; median bucket 1 to 2 mg
Route: Subcutaneous injection

Who: 41 repeat reporters on a self-logging tracker; reports span 0 to over 5 mg

Tolerance-check start

Amount: 1 to 2 mg
How often: Once daily
Route: Subcutaneous injection
Cycle: 12 to 16 weeks on
Rest: 4 or more weeks off

Timing: Before bed, fasted 2 or more hours after a meal. The 1 mg start is optional.

Titration steps for Tolerance-check start
When	Dose	U-100 units (2 mg vial + 0.5 mL water)
Weeks 1 to 2	1 mg	25 units · 0.25 mL
Weeks 3 to 12	2 mg	50 units · 0.5 mL

Morning protocol

Amount: 1 to 2 mg
How often: Once daily
Route: Subcutaneous injection
Cycle: 3 to 6 months

Timing: Morning, fasted. Start at 1 mg, then move to 2 mg.

IGF-1 guided bedtime dose

Amount: 1 to 2 mg
How often: Once daily, before bed
Route: Subcutaneous injection

Timing: Fasted 2 or more hours. 2 mg is standard; drop to 1 mg if IGF-1 is above range. The guide sees no benefit above 2 mg.

Daily or 5 on, 2 off

Amount: 2 mg
How often: Once daily, or 5 days on and 2 off
Route: Subcutaneous injection

Doses shown are what sources report, labelled by origin. Not medical advice.

Community-reported amounts

The Tesamorelin amounts people mention most on Reddit, by goal. Counts, not recommendations.

Tesamorelin amounts reported on Reddit, by goal, with mention counts
Goal	Most reported amounts (mentions)
Goal not stated	2 mg (105), 1 mg (104), 0.5 mg (18), 1.5 mg (9)
Weight loss	1 mg (37), 2 mg (34), 0.5 mg (7), 500 mcg (4)
Muscle growth	1 mg (9), 2 mg (9), 500 mcg (2)

From 900 Reddit posts and comments, last mined Oct 23, 2026.

Tesamorelin dosage chart by vial size

Units to draw for the doses sources cite most, at every vial size and water volume.

Tesamorelin: concentration and U-100 syringe units for each vial size and water volume
Water	Strength	1 mgdose, units	1.4 mgdose, units	2 mgdose, units
2 mg vial
0.5 mLRegulatory	4 mg/mL	250.25 mL	350.35 mL	500.5 mL
1 mLCompetitor guide	2 mg/mL	500.5 mL	700.7 mL	1001 mL
5 mg vial
1 mLCompetitor guide	5 mg/mL	200.2 mL	280.28 mL	400.4 mL
2 mLCompetitor guide	2.5 mg/mL	400.4 mL	560.56 mL	800.8 mL
2.5 mLCompetitor guide	2 mg/mL	500.5 mL	700.7 mL	1001 mL
10 mg vial
3 mLCompetitor guide	3.333 mg/mL	300.3 mL	420.42 mL	600.6 mL
20 mg vial
0.5 mLRegulatory^†	40 mg/mL	2.50.025 mL	3.50.035 mL	50.05 mL
1 mLCompetitor guide^†	20 mg/mL	50.05 mL	70.07 mL	100.1 mL
1.3 mLRegulatory^†	15.385 mg/mL	6.50.065 mL	9.10.091 mL	130.13 mL
2 mLCompetitor guide^†	10 mg/mL	100.1 mL	140.14 mL	200.2 mL
2.5 mLCompetitor guide^†	8 mg/mL	12.50.125 mL	17.50.175 mL	250.25 mL
3 mLCompetitor guide^†	6.667 mg/mL	150.15 mL	210.21 mL	300.3 mL

Units are on a U-100 insulin syringe (100 units = 1 mL). U-50 and U-30 barrels read the same units.† Water volume sourced for a different vial size. The math is exact either way.Water volumes from

Doses shown are what sources report, labelled by origin. Not medical advice.

Calculate with this peptideYour vial, your water, your dose: Tesamorelin in syringe units, with the math shown.

Mixing Tesamorelin

Diluent: Bacteriostatic water (research vials); the Egrifta kits supply their own diluent

Water volumes sources use: 0.5 mL, 1 mL, 1.3 mL, 2 mL, 2.5 mL, 3 mL

Egrifta SV: 2 mg vial plus 0.5 mL supplied sterile water, draw 0.35 mL for a 1.4 mg dose, discard the rest. Egrifta WR: 11.6 mg vial plus 1.3 mL supplied bacteriostatic water, draw 0.16 mL for 1.28 mg; one vial covers 7 daily doses. A 5 mg tesamorelin plus 5 mg ipamorelin blend takes 2 or 3 mL.

Tesamorelin dosage questions

How much tesamorelin per day?

Trials used 2 mg once daily. The current labels use 1.4 mg (Egrifta SV) or 1.28 mg (Egrifta WR). All three give the same exposure, so do not compare the raw mg across formulations.

Is 1 mg enough?

Some protocols start at 1 mg, and trials have used 1 or 2 mg. The visceral-fat results come from 2 mg.

How much belly fat does it remove?

In adults with HIV lipodystrophy, visceral fat fell about 15% over 26 weeks versus placebo, and 17.5% by week 52 in those who stayed on it. Waist size in that group was down 3.4 cm. Fat under the skin did not change.

How much per week?

Seven daily doses. Some protocols run 5 days a week instead.

What is the dose in a tesamorelin and ipamorelin blend?

Guides range widely, from about 100 mcg to 1 mg of tesamorelin per night, because ipamorelin rises with it in a 1:1 blend. That is the biggest dosing inconsistency for this compound. Separate vials let you keep tesamorelin at a trial dose.

How much water for a 10 mg vial?

One guide uses 3 mL. Use the calculator to turn your dose into syringe units.

How long does a mixed vial last?

Egrifta WR: 7 days after mixing. Egrifta SV: use right away. Research-vial guides say anywhere from 5 days to 30 days.

Sources for these doses

14 sources, each checked by date. Record updated Oct 23, 2026. Numbers are restated in our own words and labelled by where they came from.

Clinical study2

Metabolic effects of a GRF in HIV (Falutz NEJM 2007)PubMed · checked Oct 23, 2026
Tesamorelin pooled Phase 3 (Falutz 2010)PubMed · checked Oct 23, 2026

Regulatory2

Egrifta SV labelDailyMed · checked Oct 23, 2026
Egrifta WR labelDailyMed · checked Oct 23, 2026

Competitor guide8

Tesamorelin dosage chartPeptidesExplorer · checked Oct 23, 2026
Tesamorelin dosage guidePeptideDeck · checked Oct 23, 2026
Tesamorelin dosage guideBodyHackGuide · checked Oct 23, 2026
Tesamorelin protocolPathToPeptides · checked Oct 23, 2026

Community-reported2

Performance-enhancing peptides modulating GH-IGF1 axis (Dominikowski 2026)PMC · checked Oct 23, 2026
Tesamorelin (self-logged doses)PeptIQ · checked Oct 23, 2026

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