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BPC-157 vs TB-500

Updated 11 sources

Key differences

  1. 1BPC-157 is 15 amino acids and works locally on repair, blood vessels and the gut. TB-500 is a 7 amino acid fragment thought to act through cell migration across the body.
  2. 2BPC-157 is dosed daily and has an oral option. TB-500 is dosed once or twice a week by injection.
  3. 3No head-to-head study exists.
  4. 4TB-500 is thought to act body-wide through cell migration and is dosed once or twice a week. BPC-157 works locally on repair and the gut and is dosed daily.

Side by side

Facts from each record, in the same words as their own pages.
BPC-157 and TB-500 side by side
BPC-157TB-500
Category
  • Healing & recovery
  • Healing & recovery
Evidence
  • Limited human data
  • Animal data only
FDA status
  • Not FDA approvedRegulatory
  • Not FDA approvedRegulatory
WADA
  • Prohibited
  • Prohibited
Half-life
  • Under 30 minutes for the intact peptide in rats and dogs. No human data. The 4-hour figure on many sites has no primary source.Competitor guide
  • Not established in humans for the fragment. Full-length thymosin beta-4 by IV lasted longer at higher doses; one guide cites 0.5 to 2.1 hours.Clinical study
Routes
  • Subcutaneous injection, Oral
  • Subcutaneous injection, Intramuscular injection
Forms
  • Vial (powder), Capsule, Tablet
  • Vial (powder)
Reported doses
  • 100 to 750 mcg (subcutaneous injection)
  • 1.6 to 10 mcg/kg (subcutaneous injection)
  • 250 to 1,000 mcg (oral)
  • 1 to 5 mg (subcutaneous injection)
  • 2 to 2.5 mg (intramuscular injection)
  • 500 to 1,000 mcg (subcutaneous injection)
Most cited frequency
  • Once daily
  • Twice weekly
Vial sizes
  • 5 mg, 10 mg, 20 mg, 30 mg, 40 mgCompetitor guide
  • 2 mg, 5 mg, 10 mgCompetitor guide
Mixed vial keeps
  • Fridge at 2 to 8 C, dark, never frozen.Competitor guide
  • Fridge at 2 to 8 C, dark, never frozen.Competitor guide
Protocols on file
  • 23
  • 19

Doses shown are what sources report, labelled by origin. Not medical advice.

Read each in full

Sources

11 sources, each checked by date. Record updated Oct 23, 2026. Numbers are restated in our own words and labelled by where they came from.

Regulatory3

  1. FDA to remove 12 peptides from Category 2Frier Levitt · checked Oct 23, 2026
  2. An FDA committee just voted in favor of peptidesTIME, via a news report · checked Oct 23, 2026
  3. FDA panel votes to loosen restrictions for four peptidesPharmExec, via a news report · checked Oct 23, 2026

Competitor guide5

  1. BPC-157 protocolpeptidedosingprotocols.com · checked Oct 23, 2026
  2. BPC-157 overviewpeptides.org · checked Oct 23, 2026
  3. TB-500 protocolpeptidedosingprotocols.com · checked Oct 23, 2026
  4. TB-500 vs BPC-157peptides.org · checked Oct 23, 2026