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Animal data onlyNot FDA approved

KPV dosage

Also known as: Lys-Pro-Val · Alpha-MSH (11-13) · MSH 11-13 · KPV acetate · KPV free base

Updated 29 sources

Every KPV protocol on file, 18 in all, labelled by where each number came from. 1 have titration steps, each step is worked out in U-100 units for a 10 mg vial + 2 mL water.

KPV dosage by goal

Grouped by goal. Each protocol shows the amount, how often, cycle and rest as the source states them, with every titration step.

Intranasal2

Intranasal

Amount
250 mcg
How often
Twice daily
Route
Nasal
Cycle
2 to 4 weeks

Intranasal (daily total)

Amount
200 to 800 mcg
How often
200 to 400 mcg a day; advanced 400 to 800 mcg
Route
Nasal

Other protocols: injected9

Titration

Amount
200 to 500 mcg
How often
Once daily, stepping up weekly
Route
SubQ, vial (powder)
Cycle
8 to 12 weeks, up to 16

Timing: Any consistent time.

Titration steps for Titration
WhenDoseU-100 units (10 mg vial + 2 mL water)
Week 1200 mcg4 units · 0.04 mL
Week 2300 mcg6 units · 0.06 mL
Week 3400 mcg8 units · 0.08 mL
Weeks 4 to 8500 mcg10 units · 0.1 mL

Conservative

Amount
250 mcg
How often
Once daily
Route
SubQ, vial (powder)
Cycle
2 weeks, then reassess

Standard

Amount
500 mcg
How often
Once daily
Route
SubQ, vial (powder)
Cycle
4 weeks, then reassess

Timing: Any consistent time; no built-in rest days, since the animal work dosed continuously.

Flare

Amount
500 mcg
How often
Twice daily, morning and evening
Route
SubQ, vial (powder)
Cycle
2 to 4 weeks at most

Step-down after a course

Amount
250 mcg
How often
Every other day
Route
SubQ, vial (powder)

Who: After a 4 to 8 week course.

Daily range

Amount
200 to 500 mcg
How often
Once daily
Route
SubQ, vial (powder)
Cycle
4 to 6 weeks

Open-ended daily

Amount
200 to 400 mcg
How often
Daily until the desired result
Route
SubQ, vial (powder)

Once or twice daily

Amount
200 to 500 mcg
How often
Once or twice daily, up to 500 mcg twice daily
Route
SubQ, vial (powder)
Cycle
4 to 8 weeks

High outlier

Amount
0.5 to 2 mg
How often
Once or twice daily, up to 5 mg a day
Route
SubQ, vial (powder)
Cycle
6 to 12 weeks
Rest
2 to 4 weeks off

Note: One guide's scale, 2 to 10 times higher than the rest, with no source given.

Other protocols: oral, capsule5

Gut (oral)

Amount
200 to 500 mcg
How often
Once daily
Route
Oral, capsule

Timing: Empty stomach, 30 minutes before food, because food peptides compete for the PepT1 transporter.

Oral split dose

Amount
100 to 250 mcg
How often
Morning and evening
Route
Oral, capsule

Timing: With meals, which contradicts the same site's empty-stomach advice.

Oral, common

Amount
0.5 to 2 mg
How often
500 mcg twice daily is common; range once or twice daily
Route
Oral, capsule

Timing: Empty stomach for body-wide effects, with food to target the gut.

Oral chart

Amount
250 mcg
How often
Twice daily
Route
Oral, capsule

Oral ladder (daily total)

Amount
0.5 to 5 mg
How often
500 mcg, then 1 mg, then 1 to 2 mg split; advanced 2 to 5 mg a day
Route
Oral, capsule

Timing: Empty stomach; delayed-release capsules to reach the colon.

Other protocols: topical1

Topical

Amount
7.5 mg
How often
Twice daily
Route
Topical

Other protocols: other route1

Rectal, ulcerative colitis

Amount
1 to 2 mg
How often
Nightly
Route
Other route

Who: One source only. Given in 50 to 100 mL of saline.

Doses shown are what sources report, labelled by origin. Not medical advice.

Community-reported amounts

The KPV amounts people mention most on Reddit, by goal. Counts, not recommendations.
KPV amounts reported on Reddit, by goal, with mention counts
GoalMost reported amounts (mentions)
Goal not stated500 mcg (15), 250 mcg (11), 10 mg (8), 400 mcg (8)
Gut health500 mcg (8), 250 mcg (6), 1 mg (3), 0.5 mg (2)
Injury recovery200 mcg (6), 250 mcg (6), 400 mcg (5), 500 mcg (3)
From 900 Reddit posts and comments, last mined Oct 23, 2026.

KPV dosage chart by vial size

Units to draw for the doses sources cite most, at every vial size and water volume.
KPV: concentration and U-100 syringe units for each vial size and water volume
WaterStrength200 mcgdose, units250 mcgdose, units500 mcgdose, units
5 mg vial
1 mLCompetitor guide5 mg/mL40.04 mL50.05 mL100.1 mL
2 mLCompetitor guide2.5 mg/mL80.08 mL100.1 mL200.2 mL
10 mg vial
2 mLCompetitor guide5 mg/mL40.04 mL50.05 mL100.1 mL
3 mLCompetitor guide3.333 mg/mL60.06 mL7.50.075 mL150.15 mL
Units are on a U-100 insulin syringe (100 units = 1 mL). U-50 and U-30 barrels read the same units.Water volumes from

Doses shown are what sources report, labelled by origin. Not medical advice.

Calculate with this peptideYour vial, your water, your dose: KPV in syringe units, with the math shown.

Mixing KPV

Diluent: Bacteriostatic water

Water volumes sources use: 1 mL, 2 mL, 3 mL

10 mg is the most common vial, usually in 3 mL glass. The solution should be clear and colourless. Oral capsules are sold at 500 mcg to 1 mg or 500 mcg to 2 mg.

If you miss a dose

Skip it; do not double the next dose.

KPV dosage questions

What is the typical dose?

Most guides land at 200 to 500 mcg a day. The full spread is 200 mcg to 2 mg per dose. One guide argues that more than 500 mcg buys nothing documented, since KPV blocks NF-kB at about 10 nM in cells and 500 mcg already gives about 0.5 uM in plasma.

How many units is 500 mcg?

With 10 mg in 2 mL, 500 mcg is 10 units on a U-100 syringe. Use the calculator for other mixes.

Sources for these doses

14 sources, each checked by date. Record updated Oct 23, 2026. Numbers are restated in our own words and labelled by where they came from.

Vendor guide2

  1. KPV 10 mg product pageVendor product page · checked Oct 23, 2026
  2. KPV 10 mg product pageVendor product page · checked Oct 23, 2026

Competitor guide12

  1. KPV 10 mg vial dosage protocolpeptidedosages.com · checked Oct 23, 2026
  2. KPV peptidepeptidedosages.com · checked Oct 23, 2026
  3. KPV dosage chartpeptidedeck.com · checked Oct 23, 2026
  4. KPV protocolpeptidedosingprotocols.com · checked Oct 23, 2026

Back to the full KPV page for side effects, storage, stacks and legal status.