Also known as: Pitocin · Syntocinon · Love hormone · Oxytocin nasal spray · Oxytocin acetate
Updated 22 sources
Every Oxytocin protocol on file, 13 in all, labelled by where each number came from.
Who: PeptIQ app users logging research-vial injections; 30 users. No trial tested subcutaneous oxytocin for mood or social effects.
Note: Logged doses span 0 to 400 mcg. One guide argues injected oxytocin does not reach the brain the way a nasal dose does.
Who: Research-use protocols collected by one dosing guide, in three tiers: 100, 200 to 300 and 400 to 500 mcg. Several times higher than what app users log.
Note: The guide says these ranges have no human efficacy data and that subQ dosing should not be expected to reproduce nasal effects.
Who: Hospital use after delivery of the placenta, per the Pitocin label. Shown so readers can see the approved scale; not a self-use dose.
Note: The label gives USP units. Labor induction is an IV drip started at 0.5 to 1 milliunit per minute and raised by 1 to 2 milliunits per minute every 30 to 60 minutes; rates above 9 to 10 milliunits per minute are rarely needed at term. For bleeding after birth the IV option is 10 to 40 units added to the running drip (max 40 units per 1,000 mL). The calculator does not take infusion rates.
Who: Mostly healthy adults, 79% men, across 38 randomized trials from 1990 to 2010 (1,529 people).
Timing: In a spinal-fluid study, 24 IU took up to 75 minutes to raise levels around the brain, while blood levels peaked at 15 minutes.
Who: 29 healthy couples in a naturalistic study. Drive, arousal and erection did not change; orgasm intensity and contentment after sex rose, with small to moderate effects.
Who: 30 pre- and postmenopausal women with sexual dysfunction, crossover trial. Scores improved on oxytocin and on placebo alike, with no significant difference between them.
Who: 61 adults with obesity in a randomized trial. No difference in weight change vs placebo (0.20 vs 0.26 kg), though people ate less at a test meal.
Who: Adults using compounded or home-made nasal spray before a social window, per dosing guides. Not tested as a treatment.
Timing: Guides say 30 to 75 minutes before the event. One guide starts at 18 IU to gauge response before 24 IU.
Who: Adults or couples using nasal spray before sex, per a dosing guide. Some couples dose together.
Note: In trials, nasal oxytocin did not raise desire or arousal; guides call PT-141 the stronger libido tool.
Who: Self-reported in community posts gathered from r/Nootropics, r/Peptides and Bluelight. The most common community protocol.
Who: Self-reported in community posts; some say this lower dose is enough for anxiety.
Who: Self-reported by people on physician-prescribed compounded troches. No trial compares sublingual and nasal dosing.
Note: One guide says compounded troches often carry low hundreds of IU per dose, far above this range, with limited human data.
Who: A research vendor's reference dose for study design, given for nasal or subcutaneous use.
Note: The vendor equates this to about 10 to 25 IU, using 500 IU per mg; at the European Pharmacopoeia's 600 IU per mg it is 12 to 30 IU.
Doses shown are what sources report, labelled by origin. Not medical advice.
| Water | Strength | 25 mcgdose, units | 50 mcgdose, units | 100 mcgdose, units |
|---|---|---|---|---|
| 2 mg vial | ||||
| 2 mLCompetitor guide | 1 mg/mL | 2.50.025 mL | 50.05 mL | 100.1 mL |
| 3 mLCompetitor guide | 0.667 mg/mL | 3.80.038 mL | 7.50.075 mL | 150.15 mL |
| 5 mg vial | ||||
| 2 mLVendor guide | 2.5 mg/mL | 10.01 mL | 20.02 mL | 40.04 mL |
| 3 mLCompetitor guide | 1.667 mg/mL | 1.50.015 mL | 30.03 mL | 60.06 mL |
| 10 mg vial | ||||
| 2.5 mLVendor guide | 4 mg/mL | 0.60.006 mLunder 1 unit | 1.30.013 mL | 2.50.025 mL |
Doses shown are what sources report, labelled by origin. Not medical advice.
Calculate with this peptideYour vial, your water, your dose: Oxytocin in syringe units, with the math shown.Diluent: Bacteriostatic water
Water volumes sources use: 2 mL, 2.5 mL, 3 mL
Vials are sold in mg; studies and sprays dose in IU. This page uses 600 IU per mg (about 1.67 mcg per IU), the European Pharmacopoeia labelling convention, which the WHO International Standard (12.5 IU in about 21 mcg) matches. One vendor and one guide use 500 IU per mg, which puts about 20% more peptide in each IU dose. Purity varies, so treat mg-to-IU as approximate. SubQ doses of 20 to 50 mcg come out at 2 syringe units or less at these mixes, below what the vendor says a U-100 syringe reads well.
For a daily compounded spray, one pharmacy says skip the missed dose if the next one is within 6 hours, and never double up. For on-demand use there is nothing to make up.
24 IU is the research standard. A review of 38 trials covered 18 to 40 IU, mostly as single doses. Community users report 20 to 40 IU once daily or before social events, and 10 to 20 IU for daily low-dose use.
It varies a lot and no trial backs any of it. PeptIQ app users most often log 25 to 50 mcg per injection (range 0 to 400 mcg). One guide collects community protocols of 100 to 500 mcg once daily, and one vendor lists 20 to 50 mcg. The same guide argues injected oxytocin does not reach the brain the way nasal spray does.
2 mL (one vendor) or 3 mL (one guide); guides use 2 to 3 mL for 2 mg and 5 mg vials. At small doses the draw can fall under 2 units, so a finer 30-unit syringe helps. Enter your exact vial and water in a calculator.
About 1.67 mcg. The European Pharmacopoeia sets 1 mg of oxytocin as 600 IU for labelling, and the WHO International Standard (12.5 IU in about 21 mcg) agrees within 1%; this page uses 600 IU per mg. One vendor and one dosing guide say about 2 mcg per IU (1 mg is about 500 IU), which would put about 20% more peptide in each IU dose. Research vials vary in purity too, so dose by what your product is labeled in when you can.
14 sources, each checked by date. Record updated Oct 24, 2026. Numbers are restated in our own words and labelled by where they came from.
Back to the full Oxytocin page for side effects, storage, stacks and legal status.