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Limited human dataNot FDA approved

Pinealon dosing

Also known as: EDR peptide · Glu-Asp-Arg · H-Glu-Asp-Arg-OH · L-Glutamyl-L-aspartyl-L-arginine · Пинеалон · Peptide complex AC-5

Updated 35 sources

Every Pinealon protocol on file, 10 in all, labelled by where each number came from. 2 have titration steps, each step is worked out in U-100 units for a 20 mg vial + 3 mL water.

Pinealon dosing by goal

Grouped by goal. Each protocol shows the amount, how often, cycle and rest as the source states them, with every titration step.

Oral, capsule2

Oral capsules, Russian worker study

Amount
100 mcg
How often
One capsule twice a day
Route
Oral, capsule
Cycle
2 weeks

Who: Locomotive crew workers in a Russian study (group size not given in the abstract)

Note: The only human dose we found stated in PubMed. The abstract gives no group size or control. The retail supplement label says 1 to 2 capsules 1 to 2 times a day with meals for 10 to 30 days, repeated after 4 to 6 months, without stating the peptide amount.

Oral capsule (guide)

Amount
20 mg
How often
One capsule a day, usually in the morning
Route
Oral, capsule
Cycle
10 to 20 days
Rest
2 to 3 months apart, 2 to 3 cycles a year

Note: The guide says research-market capsules are commonly 20 mg and attributes 20 mg a day to published Russian reports. The one capsule dose we found in PubMed is 100 mcg, 200 times lower.

Injected6

Subcutaneous step-up (guide)

Amount
1 to 2 mg
How often
Once daily, morning or early afternoon
Route
SubQ, vial (powder)
Cycle
10 to 20 days, sometimes 28
Rest
2 to 3 months between cycles, 2 to 3 cycles a year

Timing: Morning or early afternoon

Titration steps for Subcutaneous step-up (guide)
WhenDoseU-100 units (20 mg vial + 3 mL water)
Days 1 to 51 mg15 units · 0.15 mL
Days 6 to 141.5 mg22.5 units · 0.225 mL
Days 15 to 202 mg30 units · 0.3 mL

Note: Built on a 20 mg vial with 3 mL water. The guide labels the titration an example for planning and notes some community sources run 5 to 10 mg.

Low-dose subcutaneous, weekdays (guide)

Amount
200 to 500 mcg
How often
Once daily, 5 days a week
Route
SubQ, vial (powder)
Cycle
30 days per course
Rest
Repeat every 4 to 6 months

Timing: Morning or early afternoon

Note: The same guide gives 10 to 20 mg a day for oral capsules and says no official dosing exists.

Short low-dose course (guide)

Amount
100 to 300 mcg
How often
Once daily
Route
SubQ, vial (powder)
Cycle
5 to 10 days, 1 to 2 times a year

Note: For cognition the same guide narrows it to 100 to 200 mcg a day for 5 to 10 days.

Higher subcutaneous range (guide)

Amount
2 to 10 mg
How often
Once daily, morning preferred; some split into morning and midday
Route
SubQ, vial (powder)
Cycle
10 to 20 day pulses, 2 to 4 cycles a year

Note: Typically 3 to 5 mg. The guide advises against oral use.

Daily start, then every other day (community via guide)

Amount
200 mcg
How often
Once daily in weeks 1 to 2, then every other day
Route
SubQ, vial (powder)
Titration steps for Daily start, then every other day (community via guide)
WhenDoseU-100 units (20 mg vial + 3 mL water)
Weeks 1 to 2200 mcg3 units · 0.03 mL

Note: The guide calls both phases community-reported and says no study has tested a maintenance schedule. Its math uses a 20 mg vial with 10 mL water (2 mg/mL), where 200 mcg is 10 units.

High-dose short course (community via guide)

Amount
5 to 10 mg
How often
Once daily, sometimes split into two doses
Route
SubQ, vial (powder)
Cycle
10 to 20 days, sometimes repeated a few times a year

Note: The guide says this is a convention shaped by the 10 mg vial size, not a trial dose.

Nasal, nasal spray1

Nasal, per nostril (guide)

Amount
150 to 800 mcg
How often
Once daily, into each nostril
Route
Nasal, nasal spray

Note: The amount is per nostril, so a full dose is twice this. We found no study of nasal pinealon.

Other route1

Alongside epitalon (community)

Amount
1 to 2.5 mg
How often
Once daily or nightly
Route
Other route
Cycle
10 to 20 days

Note: Reports on Reddit: 1 mg daily with 0.5 mg epitalon, 2.5 mg nightly with 1 mg epitalon for 20 nights, and 1 mg for 10 days alongside N-acetyl epitalon. The posts we read do not always state the route.

Doses shown are what sources report, labelled by origin. Not medical advice.

Pinealon dosing chart by vial size

Units to draw for the doses sources cite most, at every vial size and water volume.
Pinealon: concentration and U-100 syringe units for each vial size and water volume
WaterStrength200 mcgdose, units2 mgdose, units10 mgdose, units
10 mg vial
1 mLCompetitor guide10 mg/mL20.02 mL200.2 mL1001 mL
2 mLCompetitor guide5 mg/mL40.04 mL400.4 mL2002 mL2 draws
20 mg vial
2 mLCompetitor guide10 mg/mL20.02 mL200.2 mL1001 mL
3 mLCompetitor guide6.667 mg/mL30.03 mL300.3 mL1501.5 mL2 draws
4 mLCompetitor guide5 mg/mL40.04 mL400.4 mL2002 mL2 draws
10 mLCompetitor guide2 mg/mL100.1 mL1001 mL5005 mL5 draws
Units are on a U-100 insulin syringe (100 units = 1 mL). U-50 and U-30 barrels read the same units.Water volumes from

Doses shown are what sources report, labelled by origin. Not medical advice.

Calculate with this peptideYour vial, your water, your dose: Pinealon in syringe units, with the math shown.

Mixing Pinealon

Diluent: Bacteriostatic water

Water volumes sources use: 1 mL, 2 mL, 3 mL, 4 mL, 10 mL

Pick the volume that makes your dose easy to draw. Low doses (100 to 300 mcg) read better on a dilute vial; 5 to 10 mg doses need a strong one. Swirl gently, do not shake.

Pinealon dosing questions

What dose has been used in people?

The only human dose we found stated in PubMed is oral: one 100 mcg capsule twice a day for two weeks, in a Russian study of train crew workers.

What dose do injection guides use?

They disagree widely: 100 to 300 mcg, 200 to 500 mcg, 1 to 2 mg, or 2 to 10 mg a day. None comes from a dose-finding trial.

How much water for a 20 mg vial?

3 mL is the common choice and gives about 6.67 mg/mL, where 1 unit is about 66.7 mcg. Guides also use 2 mL (10 mg/mL) or 10 mL (2 mg/mL).

How much water for a 10 mg vial?

1 mL gives 10 mg/mL, so 5 mg is 50 units. 2 mL gives 5 mg/mL.

How long is a cycle?

Guides run 5 to 30 days. The Russian supplement label says 10 to 30 days, repeated after 4 to 6 months; the only human course in PubMed lasted 2 weeks.

How long does mixed pinealon last?

In the fridge at 2 to 8 C, guides give 14 to 30 days. Use 14 days to stay inside all of them.

Sources for these doses

10 sources, each checked by date. Record updated Oct 24, 2026. Numbers are restated in our own words and labelled by where they came from.

Competitor guide4

  1. Pinealon quick startpeptidedosingprotocols.com · checked Oct 24, 2026
  2. Pinealon dosingpeptideprotocolwiki.com · checked Oct 24, 2026
  3. Pinealon dosage guidemypeptidematch.com · checked Oct 24, 2026
  4. Pinealon vs Epithalonbodyhackguide.co · checked Oct 24, 2026

Community-reported5

  1. Pinealon dosing protocol: 20 mg vialmypeptidematch.com, via a competitor guide · checked Oct 24, 2026
  2. Pinealon dosing guidethepeptidecatalog.com, via a competitor guide · checked Oct 24, 2026
  3. Epitalon and pinealon, 2-week Garmin datar/Biohackers · checked Oct 23, 2026
  4. Comment: 1 mg epitalon with 2.5 mg pinealon for 20 nightsr/Peptides · checked Oct 23, 2026

Back to the full Pinealon page for side effects, storage, stacks and legal status.