Glossary
GHRH
Also called Growth hormone-releasing hormone, GHRH analog, GRF, Somatocrinin
The hormone from the hypothalamus that tells the pituitary to release growth hormone. Sermorelin, tesamorelin and CJC-1295 are GHRH analogs.
In more detail
GHRH works through its own receptor on the pituitary. Analogs keep the active front part of the molecule and modify it to last longer. Tesamorelin is FDA approved for a specific fat-reduction use. Sermorelin was sold in the US as Geref and later discontinued; FDA determined in 2013 that it was not withdrawn for safety or effectiveness reasons. CJC-1295 has never been approved.
GHRH analogs are often paired with a GHRP because the two act on different receptors and community protocols treat them as complementary.
Why it matters
Knowing which side of the pathway a compound works on explains why "CJC-1295 plus ipamorelin" blends exist. Under the WADA list, GHRH analogs are banned in sport at all times.
Related terms
- GHRPA family of small synthetic peptides that trigger growth hormone release through the ghrelin receptor. GHRP-2, GHRP-6 and ipamorelin are examples.
- SecretagogueAnything that makes a gland secrete a hormone. In peptide talk it almost always means a growth hormone secretagogue: a compound that prompts your own pituitary to release growth hormone.
- Peptide blendTwo or more peptides sold together in one vial, such as BPC-157 with TB-500. Every draw delivers all of them in a fixed ratio.
- WADA S0The catch-all class on the World Anti-Doping Agency list: any substance with no current approval for human therapeutic use is banned in sport at all times, even if it is not named.
Peptides where this comes up
Sources
Each source is labeled by where the information comes from. How we label sources
- Reference workGrowth hormone-releasing hormone(opens in a new tab)
Wikipedia · checked
- RegulatoryEgrifta SV (tesamorelin) label(opens in a new tab)
DailyMed · checked
- RegulatoryDetermination that GEREF (sermorelin acetate) injection was not withdrawn from sale for reasons of safety or effectiveness(opens in a new tab)
Federal Register · checked
- RegulatoryProhibited List 2026(opens in a new tab)
World Anti-Doping Agency · checked
Updated