Oral, standard start (competitor guides)
Who: Adults following competitor dosing guides. No human dose has ever been tested in a trial.
Timing: In the morning, with food.
Also known as: 5 amino 1mq · 5-Amino-1-methylquinolinium · 5-Amino-1-methylquinolinium iodide · 5A1MQ · 5-AMQ · 5-Am-1MQ · Amino 1MQ
Updated 40 sources
Every 5-Amino-1MQ protocol on file, 8 in all, labelled by where each number came from.
Who: Adults following competitor dosing guides. No human dose has ever been tested in a trial.
Timing: In the morning, with food.
Who: Self-reported by Reddit users, including one type 1 diabetic who reports better insulin sensitivity alongside MOTS-c. No human dose has ever been tested in a trial.
Timing: Each morning.
Who: Adults following competitor dosing guides who step up from 50 mg a day. No human dose has ever been tested in a trial.
Timing: Split between morning and midday.
Who: Self-reported by Reddit users, often alongside retatrutide and MOTS-c. One cyclist reports 50 to 150 mg a day for endurance. Another says 50 mg barely did anything. No human dose has ever been tested in a trial.
Timing: Morning and midday.
Who: One Reddit user stacking with NAD+ and tirzepatide. No human dose has ever been tested in a trial.
Timing: Reached by week 3 after titrating up. Taken about 30 minutes after an NAD+ injection.
Who: Adults following competitor dosing guides for the 50 mg vial. No human dose has ever been tested in a trial.
Timing: In the morning.
Who: Self-reported by Reddit users, often stacked with MOTS-c, SLU-PP-332 or retatrutide. No human dose has ever been tested in a trial.
Timing: Morning or before a workout. One user found an evening dose kept them up late.
Who: A vocal minority of Reddit users who argue real effects need 50 mg or more. One user who ran 25 mg a day for 6 weeks says it did nothing. No human dose has ever been tested in a trial.
Doses shown are what sources report, labelled by origin. Not medical advice.
| Goal | Most reported amounts (mentions) |
|---|---|
| Goal not stated | 50 mg (19), 500 mcg (14), 5 mg (9), 10 mg (9) |
| Weight loss | 5 mg (4), 50 mg (3), 84 mg (2) |
| Longevity and energy | 5 mg (2) |
| Water | Strength | 2.5 mgdose, units | 5 mgdose, units | 10 mgdose, units |
|---|---|---|---|---|
| 5 mg vial | ||||
| 1 mLCompetitor guide† | 5 mg/mL | 500.5 mL | 1001 mL | 2002 mL2 draws |
| 3 mLCompetitor guide† | 1.667 mg/mL | 1501.5 mL2 draws | 3003 mL3 draws | 6006 mL6 draws |
| 4 mLCompetitor guide† | 1.25 mg/mL | 2002 mL2 draws | 4004 mL4 draws | 8008 mL8 draws |
| 10 mg vial | ||||
| 1 mLCompetitor guide | 10 mg/mL | 250.25 mL | 500.5 mL | 1001 mL |
| 3 mLCommunity-reported | 3.333 mg/mL | 750.75 mL | 1501.5 mL2 draws | 3003 mL3 draws |
| 50 mg vial | ||||
| 3 mLCompetitor guide | 16.667 mg/mL | 150.15 mL | 300.3 mL | 600.6 mL |
| 4 mLCompetitor guide | 12.5 mg/mL | 200.2 mL | 400.4 mL | 800.8 mL |
Doses shown are what sources report, labelled by origin. Not medical advice.
Calculate with this peptideYour vial, your water, your dose: 5-Amino-1MQ in syringe units, with the math shown.Diluent: Bacteriostatic water
Water volumes sources use: 1 mL, 3 mL, 4 mL
These sizes are injectable powder vials. Most people take 5-Amino-1MQ as oral capsules, where 50 mg per capsule is the common unit and no mixing is needed. A prefilled 50 mg pen is also reported in community posts. Guides mix the 50 mg vial with 3 to 4 mL. No water volume was found for the 5 mg vial. Oral and injected doses are on different scales, so never convert one to the other.
Guides and community posts start at 50 mg a day, usually one capsule in the morning. Many step up to 100 mg a day split into two doses, and some go to 150 mg. No human trial has tested any of these.
Dosing guides start at 2.5 mg a day and move to 5 mg a day. Reddit reports range from 0.4 mg in blends up to 50 mg a day, and one user summed up the spread as anywhere from 100 mcg to 100 mg. A claim that 12.5 mg saturates NNMT in humans has no data behind it.
Dosing guides use 3 to 4 mL of bacteriostatic water for the 50 mg vial. Enter your vial and water volume in the calculator to get the exact draw for your dose.
Guides quote 8 to 12 weeks on and 4 to 6 weeks off. No study supports any particular cycle length.
17 sources, each checked by date. Record updated Oct 23, 2026. Numbers are restated in our own words and labelled by where they came from.
Back to the full 5-Amino-1MQ page for side effects, storage, stacks and legal status.