CJC-1295 vs MK-677 (Ibutamoren)

Name: CJC-1295 vs MK-677 (Ibutamoren)
Published: 2026-10-24

Updated Oct 24, 202610 sources

Key differences

1CJC-1295 works on the GHRH receptor; MK-677 on the ghrelin receptor, so the two act on different switches.
2CJC-1295 is injected; MK-677 is swallowed.

Facts from each record, in the same words as their own pages.

CJC-1295 and MK-677 (Ibutamoren) side by side
	CJC-1295	MK-677 (Ibutamoren)
Category	GH axis	GH axis
Evidence	Limited human data	Some human trials
FDA status	Not FDA approvedRegulatory	FDA 503A Category 2Regulatory
WADA	Prohibited	Prohibited
Half-life	With DAC: 5.8 to 8.1 days in healthy adults. Without DAC: about 30 minutes per guides, never measured in humans.Competitor guide	About 4 to 6 hours, measured in beagles; no human plasma half-life in the sources.Reference work About 24 hours, per most guides. That figure tracks how long the effect lasts more than plasma levels.Competitor guide
Routes	Subcutaneous injection	Oral
Forms	Not reported	Capsule, Oral solution
Reported doses	0.4 to 2 mg (subcutaneous injection) 100 to 400 mcg (subcutaneous injection)	2 to 25 mg (oral) 0.8 to 3.2 mg/kg (oral)
Most cited frequency	1 to 2 mg a week, split into 1 or 2 injections	Once daily
Vial sizes	2 mg, 5 mgCompetitor guide	Not reported
Mixed vial keeps	Fridge, 2 to 8 °C, and avoid freeze-thaw.Competitor guide	Not reported
Protocols on file	9	16

Doses shown are what sources report, labelled by origin. Not medical advice.

10 sources, each checked by date. Record updated Oct 24, 2026. Numbers are restated in our own words and labelled by where they came from.