KPV vs LL-37

Name: KPV vs LL-37
Published: 2026-10-24

Updated Oct 24, 202610 sources

Key differences

1LL-37 is the antimicrobial. KPV antimicrobial claims rest on work from 2000, and a 2018 study found none for a modified KPV.
2LL-37 is antimicrobial and can push inflammation up; KPV is a three-amino-acid anti-inflammatory.
3They are often stacked for gut goals.

Facts from each record, in the same words as their own pages.

KPV and LL-37 side by side
	KPV	LL-37
Category	Immune, Healing & recovery	Immune, Healing & recovery
Evidence	Animal data only	Limited human data
FDA status	Not FDA approvedRegulatory	Not FDA approvedRegulatory
WADA	Not confirmed	Not confirmed
Half-life	Not published for humans. Unmodified tripeptides are cut by blood enzymes within minutes. Figures online from 15 minutes to 24 hours have no source.Competitor guide	Not measured in humans after injection. One guide cites about 15 to 30 minutes in serum, unsourced.Competitor guide About 30 minutes for the free peptide, cleared by protease breakdown, per one guide; it adds that human data are lacking.Competitor guide About 4 to 6 hours, per one guide, with no source.Competitor guide
Routes	Subcutaneous injection, Oral, Topical, Nasal, Other route	Subcutaneous injection, Topical, Other route
Forms	Vial (powder), Capsule	Vial (powder), Topical
Reported doses	200 to 500 mcg (subcutaneous injection) 0.5 to 2 mg (subcutaneous injection) 100 to 500 mcg (oral)	25 to 750 mcg (subcutaneous injection) 0.01 to 3.2 mg/mL (topical) 250 mcg (other route)
Most cited frequency	Once daily	Daily
Vial sizes	5 mg, 10 mgCompetitor guide	5 mg, 10 mgVendor guide
Mixed vial keeps	Fridge at 2 to 8 C, not frozen.Competitor guide	Fridge at 2 to 8 C, dark, never frozen.Competitor guide
Protocols on file	18	18

Doses shown are what sources report, labelled by origin. Not medical advice.

10 sources, each checked by date. Record updated Oct 24, 2026. Numbers are restated in our own words and labelled by where they came from.