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DSIP vs Ipamorelin

Updated 6 sources

Key differences

  1. 1Ipamorelin acts through growth hormone release and amplifies an existing sleep mechanism. Guides rate it better for recovery than for anxiety-driven insomnia.
  2. 2They are usually stacked rather than swapped.

Side by side

Facts from each record, in the same words as their own pages.
DSIP and Ipamorelin side by side
DSIPIpamorelin
Category
  • Sleep
  • GH axis
Evidence
  • Limited human data
  • Limited human data
FDA status
  • Not FDA approvedRegulatory
  • Not FDA approvedRegulatory
WADA
  • Not confirmed
  • Prohibited
Half-life
  • About 8 minutes in human plasma per FDA; 5 to 10 minutes in human serum in the lab and 2 to 6 minutes in animals.Regulatory
  • About 2 hours after IV infusion in healthy men. Subcutaneous half-life has not been published.Clinical study
Routes
  • Subcutaneous injection, Nasal, Intravenous (IV)
  • Subcutaneous injection
Forms
  • Vial (powder), Nasal spray
Not reported
Reported doses
  • 25 to 1,000 mcg (subcutaneous injection)
  • 20 to 40 mcg (nasal)
  • 21.3 to 21.4 mcg/kg (intravenous (iv))
  • 100 to 400 mcg (subcutaneous injection)
Most cited frequency
  • Once nightly
  • Once daily, before bed
Vial sizes
  • 2 mg, 5 mg, 10 mg, 15 mgCompetitor guide
  • 2 mg, 5 mg, 10 mgCompetitor guide
Mixed vial keeps
  • Keep the mixed vial at 2 to 8 C, away from light, and do not freeze and thaw it.Competitor guide
  • Fridge, 2 to 8 °C.Competitor guide
Protocols on file
  • 20
  • 10

Doses shown are what sources report, labelled by origin. Not medical advice.

Read each in full

Sources

6 sources, each checked by date. Record updated Oct 24, 2026. Numbers are restated in our own words and labelled by where they came from.

Clinical study1

  1. Ipamorelin PK-PD (Gobburu 1999)PubMed · checked Oct 23, 2026

Competitor guide1

  1. Peptides for sleeppeptidesexplorer.com · checked Oct 23, 2026