GHRP-2 and GHRP-6 vs Ipamorelin
Updated 9 sources
Key differences
- 1In swine, ipamorelin matched GHRP-6 on GH release. GHRP-2 was more potent per mcg but reached a lower maximum than GHRP-6.
- 2GHRP-2 and GHRP-6 raised ACTH and cortisol; ipamorelin did not.
- 3Hunger: moderate with GHRP-2, strong with GHRP-6, mild with ipamorelin per guides.
- 4Half-life: about 0.55 hours for GHRP-2, about 2.5 hours for GHRP-6, about 2 hours for ipamorelin.
- 5In animals, ipamorelin matched GHRP-6 on GH release. GHRP-2 and GHRP-6 raised ACTH and cortisol; ipamorelin did not.
- 6Hunger is mild with ipamorelin per guides, and strong with GHRP-6.
Side by side
Facts from each record, in the same words as their own pages.
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Doses shown are what sources report, labelled by origin. Not medical advice.
Read each in full
Sources
9 sources, each checked by date. Record updated Oct 24, 2026. Numbers are restated in our own words and labelled by where they came from.
Clinical study4
- Ipamorelin, the first selective growth hormone secretagogue (Raun 1998)PubMed · checked Oct 23, 2026
- GHRP-2, like ghrelin, increases food intake (Laferrere 2005)PubMed · checked Oct 23, 2026
- Performance-enhancing peptides modulating GH-IGF1 axis (Dominikowski 2026)PMC · checked Oct 23, 2026
- Ipamorelin PK-PD (Gobburu 1999)PubMed · checked Oct 23, 2026
Regulatory2
- Certain bulk drug substances that may present significant safety risksFDA · checked Oct 24, 2026
- 503A bulk drug substance categories (May 14, 2026)FDA · checked Oct 24, 2026
Competitor guide3
- GHRP-6PeptidesExplorer · checked Oct 23, 2026
- IpamorelinPeptidesExplorer · checked Oct 23, 2026
- GHRP-6 5 mg vialPeptideDosages · checked Oct 23, 2026