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HGH Fragment 176-191 vs Ipamorelin

Updated 6 sources

Key differences

  1. 1Ipamorelin makes the pituitary release your own GH; the fragment releases no GH.
  2. 2People often pair them, fragment for fat and ipamorelin for recovery and sleep.

Side by side

Facts from each record, in the same words as their own pages.
HGH Fragment 176-191 and Ipamorelin side by side
HGH Fragment 176-191Ipamorelin
Category
  • Weight loss, GH axis
  • GH axis
Evidence
  • Animal data only
  • Limited human data
FDA status
  • Not FDA approvedRegulatory
  • Not FDA approvedRegulatory
WADA
  • Prohibited
  • Prohibited
Half-life
  • About 30 minutes, per guides; no measured value for the fragment.Competitor guide
  • 15 to 20 minutes, per another guide; also unsourced.Competitor guide
  • For the related AOD-9604: about 3 minutes after an IV dose in pigs, and 4 minutes in rat blood in a test tube.Regulatory
  • About 2 hours after IV infusion in healthy men. Subcutaneous half-life has not been published.Clinical study
Routes
  • Subcutaneous injection
  • Subcutaneous injection
Forms
  • Vial (powder)
Not reported
Reported doses
  • 250 to 1,000 mcg (subcutaneous injection)
  • 100 to 400 mcg (subcutaneous injection)
Most cited frequency
  • Once daily, morning fasted
  • Once daily, before bed
Vial sizes
  • 2 mg, 5 mg, 10 mgCompetitor guide
  • 2 mg, 5 mg, 10 mgCompetitor guide
Mixed vial keeps
  • Fridge at 2 to 8 C, use within 14 to 21 days, do not freeze, keep from light.Competitor guide
  • Fridge, 2 to 8 °C.Competitor guide
Protocols on file
  • 7
  • 10

Doses shown are what sources report, labelled by origin. Not medical advice.

Read each in full

Sources

6 sources, each checked by date. Record updated Oct 24, 2026. Numbers are restated in our own words and labelled by where they came from.

Clinical study1

  1. Ipamorelin PK-PD (Gobburu 1999)PubMed · checked Oct 23, 2026

Competitor guide2

  1. HGH Fragment 176-191: Dosage, Benefits & Safetypeptidesexplorer.com · checked Oct 24, 2026
  2. HGH Fragment 176-191 (HGH Frag)peptide-db.com · checked Oct 24, 2026