LL-37 vs TB-500

Name: LL-37 vs TB-500
Published: 2026-10-24

Updated Oct 24, 20269 sources

Key differences

1TB-500 is for soft-tissue recovery and is not antimicrobial. LL-37 is antimicrobial and dosed in micrograms, not milligrams.

Facts from each record, in the same words as their own pages.

LL-37 and TB-500 side by side
	LL-37	TB-500
Category	Immune, Healing & recovery	Healing & recovery
Evidence	Limited human data	Animal data only
FDA status	Not FDA approvedRegulatory	Not FDA approvedRegulatory
WADA	Not confirmed	Prohibited
Half-life	Not measured in humans after injection. One guide cites about 15 to 30 minutes in serum, unsourced.Competitor guide About 30 minutes for the free peptide, cleared by protease breakdown, per one guide; it adds that human data are lacking.Competitor guide About 4 to 6 hours, per one guide, with no source.Competitor guide	Not established in humans for the fragment. Full-length thymosin beta-4 by IV lasted longer at higher doses; one guide cites 0.5 to 2.1 hours.Clinical study
Routes	Subcutaneous injection, Topical, Other route	Subcutaneous injection, Intramuscular injection
Forms	Vial (powder), Topical	Vial (powder)
Reported doses	25 to 750 mcg (subcutaneous injection) 0.01 to 3.2 mg/mL (topical) 250 mcg (other route)	1 to 5 mg (subcutaneous injection) 2 to 2.5 mg (intramuscular injection) 500 to 1,000 mcg (subcutaneous injection)
Most cited frequency	Daily	Twice weekly
Vial sizes	5 mg, 10 mgVendor guide	2 mg, 5 mg, 10 mgCompetitor guide
Mixed vial keeps	Fridge at 2 to 8 C, dark, never frozen.Competitor guide	Fridge at 2 to 8 C, dark, never frozen.Competitor guide
Protocols on file	18	19

Doses shown are what sources report, labelled by origin. Not medical advice.

9 sources, each checked by date. Record updated Oct 24, 2026. Numbers are restated in our own words and labelled by where they came from.