AOD-9604 vs Somatropin (HGH)

Name: AOD-9604 vs Somatropin (HGH)
Published: 2026-10-24

Updated Oct 24, 20268 sources

Key differences

1AOD-9604 did not raise IGF-1 in trials, per the company authors. Somatropin raises IGF-1.
2Somatropin is an approved drug; AOD-9604 is not.

Facts from each record, in the same words as their own pages.

AOD-9604 and Somatropin (HGH) side by side
	AOD-9604	Somatropin (HGH)
Category	Weight loss	GH axis
Evidence	Limited human data	Strong human trials
FDA status	Not FDA approvedRegulatory	FDA approved as Genotropin +7Regulatory
WADA	Prohibited	Prohibited
Half-life	About 3 minutes after an IV bolus in pigs and about 4 minutes in rat blood in vitro. No human subcutaneous data.Clinical study	About 3 hours after a subcutaneous dose in adults with GH deficiency; 0.4 hours when given IV. The longer SC figure reflects slow absorption.Regulatory 3.8 hours after a subcutaneous dose in healthy adults (Humatrope).Regulatory 2.5 to 2.8 hours after a subcutaneous dose in healthy adults (Omnitrope).Regulatory
Routes	Oral, Subcutaneous injection	Subcutaneous injection
Forms	Not reported	Vial (powder), Prefilled pen
Reported doses	0.25 to 30 mg (oral) 250 to 500 mcg (subcutaneous injection) 1 to 2 mg (subcutaneous injection)	0.15 to 0.3 mg (subcutaneous injection) 0.004 to 0.1 mg/kg (subcutaneous injection) 1 to 8 IU (subcutaneous injection)
Most cited frequency	Once daily	Once daily; raise by about 0.1 to 0.2 mg/day every 1 to 2 months
Vial sizes	2 mg, 5 mg, 10 mgCompetitor guide	5.8 mg, 5 mg, 10 mg, 4 IU, 10 IU, 12 IURegulatory
Mixed vial keeps	Keep at 2 to 8 °C, away from light, and do not freeze and thaw.Community-reported	Genotropin cartridge after mixing: fridge at 2 to 8 C for up to 28 days, protected from light.Regulatory
Protocols on file	12	10

Doses shown are what sources report, labelled by origin. Not medical advice.

8 sources, each checked by date. Record updated Oct 24, 2026. Numbers are restated in our own words and labelled by where they came from.