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HGH Fragment 176-191 vs Somatropin (HGH)

Updated 13 sources

Key differences

  1. 1Somatropin is the whole 191-amino-acid hormone; the fragment is 16 amino acids from its tail.
  2. 2Somatropin raises IGF-1 and is FDA approved for set uses; the fragment is unapproved and marketed for fat loss only.
  3. 3One guide calls stacking them redundant.
  4. 4Somatropin is the full 191-amino-acid hormone; Fragment 176-191 is a 16-amino-acid piece of its tail.
  5. 5Somatropin raises IGF-1 and has approved uses; the fragment is marketed for fat loss only and has no human trials.

Side by side

Facts from each record, in the same words as their own pages.
HGH Fragment 176-191 and Somatropin (HGH) side by side
HGH Fragment 176-191Somatropin (HGH)
Category
  • Weight loss, GH axis
  • GH axis
Evidence
  • Animal data only
  • Strong human trials
FDA status
  • Not FDA approvedRegulatory
  • FDA approved as Genotropin +7Regulatory
WADA
  • Prohibited
  • Prohibited
Half-life
  • About 30 minutes, per guides; no measured value for the fragment.Competitor guide
  • 15 to 20 minutes, per another guide; also unsourced.Competitor guide
  • For the related AOD-9604: about 3 minutes after an IV dose in pigs, and 4 minutes in rat blood in a test tube.Regulatory
  • About 3 hours after a subcutaneous dose in adults with GH deficiency; 0.4 hours when given IV. The longer SC figure reflects slow absorption.Regulatory
  • 3.8 hours after a subcutaneous dose in healthy adults (Humatrope).Regulatory
  • 2.5 to 2.8 hours after a subcutaneous dose in healthy adults (Omnitrope).Regulatory
Routes
  • Subcutaneous injection
  • Subcutaneous injection
Forms
  • Vial (powder)
  • Vial (powder), Prefilled pen
Reported doses
  • 250 to 1,000 mcg (subcutaneous injection)
  • 0.15 to 0.3 mg (subcutaneous injection)
  • 0.004 to 0.1 mg/kg (subcutaneous injection)
  • 1 to 8 IU (subcutaneous injection)
Most cited frequency
  • Once daily, morning fasted
  • Once daily; raise by about 0.1 to 0.2 mg/day every 1 to 2 months
Vial sizes
  • 2 mg, 5 mg, 10 mgCompetitor guide
  • 5.8 mg, 5 mg, 10 mg, 4 IU, 10 IU, 12 IURegulatory
Mixed vial keeps
  • Fridge at 2 to 8 C, use within 14 to 21 days, do not freeze, keep from light.Competitor guide
  • Genotropin cartridge after mixing: fridge at 2 to 8 C for up to 28 days, protected from light.Regulatory
Protocols on file
  • 7
  • 10

Doses shown are what sources report, labelled by origin. Not medical advice.

Read each in full

Sources

13 sources, each checked by date. Record updated Oct 24, 2026. Numbers are restated in our own words and labelled by where they came from.

Competitor guide5

  1. HGH Fragment 176-191 (HGH Frag)peptide-db.com · checked Oct 24, 2026
  2. HGH Fragment 176-191 Dosage: What Research Supportspeptidesexplorer.com · checked Oct 24, 2026
  3. HGH Dosage Calculator (IU to mg)peptidesexplorer.com · checked Oct 24, 2026
  4. HGH vs Peptidespeptidesexplorer.com · checked Oct 24, 2026