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Epitalon vs NAD+

Updated 8 sources

Key differences

  1. 1NAD+ is a coenzyme taken continuously, 50 to 100 mg injected 2 to 3 times a week or as oral NR or NMN. Epitalon is a pulsed peptide course.
  2. 2NAD+ precursors have Western randomized trials behind them; epitalon has none.

Side by side

Facts from each record, in the same words as their own pages.
Epitalon and NAD+ side by side
EpitalonNAD+
Category
  • Longevity, Sleep
  • Longevity, Cognitive
Evidence
  • Limited human data
  • Limited human data
FDA status
  • Not FDA approvedRegulatory
  • FDA 503A Category 1Regulatory
WADA
  • Not confirmed
  • Not confirmed
Half-life
  • Not established. A 2026 review says absorption, clearance and terminal half-life remain undefined in humans.Clinical study
  • Not established. No study reports human kinetic values for injected NAD+, per a 2026 review. In one IV study, plasma levels stayed flat for the first 2 hours of a 6-hour infusion.Clinical study
Routes
  • Subcutaneous injection, Oral, Intramuscular injection, Other route
  • Subcutaneous injection, Intramuscular injection, Intravenous (IV), Nasal
Forms
  • Vial (powder), Capsule, Nasal spray, Oral solution
  • Vial (powder), Nasal spray
Reported doses
  • 0.5 to 10 mg (subcutaneous injection)
  • 0.5 to 10 mg (oral)
  • 100 to 1,000 mcg (subcutaneous injection)
  • 25 to 500 mg (subcutaneous injection)
  • 50 to 100 mg (intramuscular injection)
  • 250 to 1,000 mg (intravenous (iv))
Most cited frequency
  • Once daily in the evening
  • Twice a week
Vial sizes
  • 10 mg, 50 mg, 100 mgCompetitor guide
  • 100 mg, 250 mg, 500 mg, 750 mg, 1,000 mg, 1,500 mgCompetitor guide
Mixed vial keeps
  • Fridge at 2 to 8 C, never frozen, no freeze-thaw.Competitor guide
  • Fridge at 2 to 8 C, out of light, never frozen.Competitor guide
Protocols on file
  • 23
  • 19

Doses shown are what sources report, labelled by origin. Not medical advice.

Read each in full

Sources

8 sources, each checked by date. Record updated Oct 23, 2026. Numbers are restated in our own words and labelled by where they came from.

Clinical study3

  1. Jain et al. 2026, epitalon and epithalamin narrative review (full text)PMC · checked Oct 23, 2026
  2. Narrative review of IV NAD+ (2026)Frontiers in Aging · checked Oct 23, 2026
  3. Grant et al. 2019, IV NAD+ pilotPMC · checked Oct 23, 2026

Competitor guide1

  1. Epitalon vs NAD+peptidedeck.com · checked Oct 23, 2026