5-Amino-1MQ vs NAD+

Name: 5-Amino-1MQ vs NAD+
Published: 2026-10-24

Updated Oct 24, 20267 sources

Key differences

1NAD+ and its precursors supply raw material. 5-Amino-1MQ blocks one clearance route for nicotinamide instead.
25-Amino-1MQ raised NAD+ in fat cells. No human measurement exists.

Facts from each record, in the same words as their own pages.

5-Amino-1MQ and NAD+ side by side
	5-Amino-1MQ	NAD+
Category	Weight loss, Longevity	Longevity, Cognitive
Evidence	Animal data only	Limited human data
FDA status	Not FDA approvedRegulatory	FDA 503A Category 1Regulatory
WADA	Prohibited	Not confirmed
Half-life	About 3.8 hours after IV and 6.9 hours after oral dosing in rats, with 38.4% oral bioavailability. No human data.Clinical study	Not established. No study reports human kinetic values for injected NAD+, per a 2026 review. In one IV study, plasma levels stayed flat for the first 2 hours of a 6-hour infusion.Clinical study
Routes	Oral, Subcutaneous injection	Subcutaneous injection, Intramuscular injection, Intravenous (IV), Nasal
Forms	Not reported	Vial (powder), Nasal spray
Reported doses	50 to 100 mg (oral) 2.5 to 50 mg (subcutaneous injection)	25 to 500 mg (subcutaneous injection) 50 to 100 mg (intramuscular injection) 250 to 1,000 mg (intravenous (iv))
Most cited frequency	Once daily	Twice a week
Vial sizes	5 mg, 10 mg, 50 mgCompetitor guide	100 mg, 250 mg, 500 mg, 750 mg, 1,000 mg, 1,500 mgCompetitor guide
Mixed vial keeps	Keep the mixed vial at 2 to 8 °C, away from light, and use it within 2 to 4 weeks.Competitor guide	Fridge at 2 to 8 C, out of light, never frozen.Competitor guide
Protocols on file	8	19

Doses shown are what sources report, labelled by origin. Not medical advice.

7 sources, each checked by date. Record updated Oct 24, 2026. Numbers are restated in our own words and labelled by where they came from.