PE-22-28 vs Selank

Name: PE-22-28 vs Selank
Published: 2026-10-24

Updated Oct 24, 20265 sources

Key differences

1PE-22-28 targets mood through TREK-1; Selank is used for anxiety through GABA-linked effects.
2Community users pair them as a mood stack.

Facts from each record, in the same words as their own pages.

PE-22-28 and Selank side by side
	PE-22-28	Selank
Category	Cognitive	Cognitive, Sleep
Evidence	Animal data only	Limited human data
FDA status	Not FDA approvedRegulatory	Not FDA approvedRegulatory
WADA	Not confirmed	Not confirmed
Half-life	Not published. Described as relatively short in serum in vitro; the 23 hour effect half-time often quoted belongs to modified analogs in mice.Clinical study	Minutes. Per the Russian label, nasal Selank shows in plasma within 30 seconds and its level falls over 5 to 5.5 minutes. Nothing shows up in urine.Regulatory
Routes	Nasal, Subcutaneous injection	Nasal, Subcutaneous injection
Forms	Vial (powder), Nasal spray	Nasal spray, Vial (powder)
Reported doses	100 to 500 mcg (nasal) 50 to 500 mcg (subcutaneous injection)	150 to 2,700 mcg (nasal) 200 to 1,000 mcg (subcutaneous injection)
Most cited frequency	Once daily, in the morning	Once daily
Vial sizes	8 mg, 10 mg, 20 mgVendor guide	5 mg, 10 mg, 30 mgCompetitor guide
Mixed vial keeps	Fridge at 2 to 8 C, away from light.Competitor guide	Guides disagree on how long mixed Selank keeps: 2 to 3 weeks, 3 to 4 weeks, or 21 to 30 days.Competitor guide
Protocols on file	8	24

Doses shown are what sources report, labelled by origin. Not medical advice.

5 sources, each checked by date. Record updated Oct 24, 2026. Numbers are restated in our own words and labelled by where they came from.