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Selank vs Selank + Semax blend

Updated 7 sources

Key differences

  1. 1Selank alone can be dosed later in the day or as needed for calm. In the blend it always comes with Semax, so evening use brings Semax's sleep risk.
  2. 2Guides and users suggest starting Selank alone for 5 to 7 days before adding Semax, which a premixed vial cannot do.

Side by side

Facts from each record, in the same words as their own pages.
Selank and Selank + Semax blend side by side
SelankSelank + Semax blend
Category
  • Cognitive, Sleep
  • Cognitive
Evidence
  • Limited human data
  • No human trials
FDA status
  • Not FDA approvedRegulatory
  • Not FDA approvedRegulatory
WADA
  • Not confirmed
  • Not confirmed
Half-life
  • Minutes. Per the Russian label, nasal Selank shows in plasma within 30 seconds and its level falls over 5 to 5.5 minutes. Nothing shows up in urine.Regulatory
  • Selank: in plasma within 30 seconds of a nasal dose, and levels fall over 5 to 5.5 minutes, per the Russian label.Regulatory
  • Semax: no human value. In rats it reaches the brain 2 minutes after a nasal dose and breaks down fast.Clinical study
Routes
  • Nasal, Subcutaneous injection
  • Subcutaneous injection, Nasal
Forms
  • Nasal spray, Vial (powder)
  • Vial (powder), Nasal spray
Reported doses
  • 150 to 2,700 mcg (nasal)
  • 200 to 1,000 mcg (subcutaneous injection)
  • 200 to 1,200 mcg (subcutaneous injection)
  • 400 to 800 mcg (subcutaneous injection)
  • 100 to 200 mcg (nasal)
Most cited frequency
  • Once daily
  • 1 to 2 times a day, at the same times each day
Vial sizes
  • 5 mg, 10 mg, 30 mgCompetitor guide
  • 10 mg, 20 mg, 40 mgCompetitor guide
Mixed vial keeps
  • Guides disagree on how long mixed Selank keeps: 2 to 3 weeks, 3 to 4 weeks, or 21 to 30 days.Competitor guide
  • Fridge at 2 to 8 C, never frozen, kept dark because Semax is light-sensitive.Competitor guide
Protocols on file
  • 24
  • 7

Doses shown are what sources report, labelled by origin. Not medical advice.

Read each in full

Sources

7 sources, each checked by date. Record updated Oct 24, 2026. Numbers are restated in our own words and labelled by where they came from.

Regulatory4

  1. Selank 0.15% nasal drops (Russian label)Vidal, via a reference work · checked Oct 24, 2026
  2. Selank instruction for use (Russian label)selank.ru (Peptogen), archived copy, via a vendor guide · checked Oct 24, 2026
  3. Certain bulk drug substances for use in compounding that may present significant safety risksFDA · checked Oct 23, 2026
  4. FDA briefing document: Semax-related bulk drug substances, PCAC July 23-24 2026FDA · checked Oct 24, 2026

Competitor guide1

  1. Russian nootropic stack: Semax + Selankpeptidedosingprotocols.com · checked Oct 24, 2026

Community-reported1

  1. Comment in Semax/Selank blend thread: try each alone firstr/Peptides · checked Oct 23, 2026